Literature DB >> 8398658

Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis.

J L Murphy1, H L Kano, P J Chenaille, S P Makker.   

Abstract

A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy. She subsequently developed fatal Pneumocystis carinii pneumonia (PCP). This is the first report of a pediatric patient whose treatment for FSGS resulted in PCP, raising the issue of PCP prophylaxis for these patients.

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Year:  1993        PMID: 8398658     DOI: 10.1007/bf00857565

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN: 0931-041X            Impact factor:   3.714


  10 in total

1.  Pneumocystis carinii pneumonia. Differences in lung parasite number and inflammation in patients with and without AIDS.

Authors:  A H Limper; K P Offord; T F Smith; W J Martin
Journal:  Am Rev Respir Dis       Date:  1989-11

2.  High-dose short-term chlorambucil for intractable sympathetic ophthalmia and Behçet's disease.

Authors:  H H Tessler; T Jennings
Journal:  Br J Ophthalmol       Date:  1990-06       Impact factor: 4.638

3.  Pneumocystis carinii pneumonia: a lethal complication of "pulse" methylprednisolone therapy.

Authors:  G A Kozeny; J P Quinn; V K Bansal; L L Vertuno; E Hano
Journal:  Int J Artif Organs       Date:  1987-09       Impact factor: 1.595

4.  Predicting risk of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children.

Authors:  R M Rutstein
Journal:  Am J Dis Child       Date:  1991-08

5.  Seizures: a significant side effect of chlorambucil therapy in children.

Authors:  S A Williams; S P Makker; W E Grupe
Journal:  J Pediatr       Date:  1978-09       Impact factor: 4.406

6.  Infectious complications with plasmapheresis in rapidly progressive glomerulonephritis.

Authors:  E J Wing; F J Bruns; D S Fraley; D P Segel; S Adler
Journal:  JAMA       Date:  1980-11-28       Impact factor: 56.272

7.  Treatment of steroid-resistant focal segmental glomerulosclerosis with pulse methylprednisolone and alkylating agents.

Authors:  S A Mendoza; V M Reznik; W R Griswold; A M Krensky; P D Yorgin; B M Tune
Journal:  Pediatr Nephrol       Date:  1990-07       Impact factor: 3.714

8.  Chlorambucil treatment of frequently relapsing nephrotic syndrome.

Authors:  W E Grupe; S P Makker; J R Ingelfinger
Journal:  N Engl J Med       Date:  1976-09-30       Impact factor: 91.245

9.  Mesangial proliferative glomerulonephritis.

Authors:  H K Bhasin; J G Abuelo; R Nayak; A R Esparza
Journal:  Lab Invest       Date:  1978-07       Impact factor: 5.662

10.  Efficacy and safety of captopril in the treatment of severe childhood hypertension: report of the International Collaborative Study Group.

Authors:  B L Mirkin; T J Newman
Journal:  Pediatrics       Date:  1985-06       Impact factor: 7.124

  10 in total
  2 in total

1.  Overcoming Hurdles to Development of a Vaccine against Pneumocystis jirovecii.

Authors:  Beth A Garvy
Journal:  Infect Immun       Date:  2017-03-23       Impact factor: 3.441

2.  The trophic life cycle stage of Pneumocystis species induces protective adaptive responses without inflammation-mediated progression to pneumonia.

Authors:  Heather M Evans; Beth A Garvy
Journal:  Med Mycol       Date:  2018-11-01       Impact factor: 4.076

  2 in total

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