Literature DB >> 8397116

Inhibition of an archaeal protein phosphatase activity by okadaic acid, microcystin-LR, or calyculin A.

K A Oxenrider1, M E Rasche, M V Thorsteinsson, P J Kennelly.   

Abstract

Soluble extracts of the methanogenic archaeon, Methanosarcina thermophila TM-1, contained a divalent metal ion-stimulated protein-serine phosphatase activity. This activity was sensitive to micromolar concentrations of okadaic acid, microcystin-LR, or calyculin A, three compounds thought to be highly specific inhibitors of the type 1/2A/2B genetic superfamily of eukaryotic protein-serine/threonine phosphatases. The observation that each of these three chemically unrelated compounds inhibited this archaeal protein phosphatase activity suggests the existence of structural homology, and perhaps even common genetic ancestry, with the type 1/2A/2B superfamily of protein-serine/threonine phosphatases found in eukaryotic organisms.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8397116     DOI： 10.1016/0014-5793(93)80355-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

Review 1.  Archaeal protein kinases and protein phosphatases: insights from genomics and biochemistry.

Authors:  Peter J Kennelly
Journal:  Biochem J       Date:  2003-03-01       Impact factor: 3.857

Review 2.  Posttranslational protein modification in Archaea.

Authors:  Jerry Eichler; Michael W W Adams
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

3.  Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon.

Authors:  J Leng; A J Cameron; S Buckel; P J Kennelly
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

4.  Molecular cloning and functional expression of a protein-serine/threonine phosphatase from the hyperthermophilic archaeon Pyrodictium abyssi TAG11.

Authors:  B Mai; G Frey; R V Swanson; E J Mathur; K O Stetter
Journal:  J Bacteriol       Date:  1998-08       Impact factor: 3.490

Review 5.  Fancy meeting you here! A fresh look at "prokaryotic" protein phosphorylation.

Authors:  P J Kennelly; M Potts
Journal:  J Bacteriol       Date:  1996-08       Impact factor: 3.490

6.  Gene cloning and expression and characterization of a toxin-sensitive protein phosphatase from the methanogenic archaeon Methanosarcina thermophila TM-1.

Authors:  B Solow; J C Young; P J Kennelly
Journal:  J Bacteriol       Date:  1997-08       Impact factor: 3.490

7.  The PPP-family protein phosphatases PrpA and PrpB of Salmonella enterica serovar Typhimurium possess distinct biochemical properties.

Authors:  L Shi; D G Kehres; M E Maguire
Journal:  J Bacteriol       Date:  2001-12       Impact factor: 3.490

8.  Open reading frame sso2387 from the archaeon Sulfolobus solfataricus encodes a polypeptide with protein-serine kinase activity.

Authors:  Brian H Lower; Peter J Kennelly
Journal:  J Bacteriol       Date:  2003-06       Impact factor: 3.490

9.  Phosphonate inhibitors of protein-tyrosine and serine/threonine phosphatases.

Authors:  H K Kole; M S Smyth; P L Russ; T R Burke
Journal:  Biochem J       Date:  1995-11-01       Impact factor: 3.857

Review 10.  Protein phosphorylation and its role in archaeal signal transduction.

Authors:  Dominik Esser; Lena Hoffmann; Trong Khoa Pham; Christopher Bräsen; Wen Qiu; Phillip C Wright; Sonja-Verena Albers; Bettina Siebers
Journal:  FEMS Microbiol Rev       Date:  2016-07-29       Impact factor: 16.408
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.