| Literature DB >> 839435 |
S J Saxena, I L Honigberg, J T Stewart, G R Keene, J J Vallner.
Abstract
Operating conditions are described for the qualitative and quantitative determination of dantrolene sodium by high-pressure liquid chromatography. A 10-mum porous silica column was employed, using carbon tetrachloride-dimethylformamide (90:10) as the mobile phase. The flow rate was 2.0 ml/min (1800 psig), and the peaks were detected at 375 nm. The analysis of a dosage form can be carried out within 30 min with an accuracy of 3.1%. The results agree favorably with those obtained with a modified spectrophotofluorometric method.Entities:
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Year: 1977 PMID： 839435 DOI： 10.1002/jps.2600660243
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534