Literature DB >> 839418

Rapid sensitive fluorometric analysis of cephalosporin antibiotics.

A B Yu, C H Nightingale, D R Flanagan.   

Abstract

A rapid and sensitive fluorometric analysis for cephalosporins, which can also be applied to penicillins, is presented. The method involves reaction with 0.1 N sodium hydroxide at 100 degrees, producing stable fluorescent products. This method was applied to cephalexin and ampicillin with detection at concentrations as low as 0.01 mug/ml.

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Year:  1977        PMID: 839418     DOI: 10.1002/jps.2600660220

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  5 in total

Review 1.  Penicillins and cephalosporins. Physicochemical properties and analysis in pharmaceutical and biological matrices.

Authors:  P C Van Krimpen; W P Van Bennekom; A Bult
Journal:  Pharm Weekbl Sci       Date:  1987-02-20

2.  Binding of cefalotin to human serum albumin.

Authors:  M O Decroix; J C Chaumeil; B Flouvat
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1984 Jul-Sep       Impact factor: 2.441

3.  Fluorimetric determination of cefuroxime in body fluids.

Authors:  Z H Al-Rawi; S Tabaqchali
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191

4.  High-performance liquid chromatographic method for determination of cefmetazole in human serum.

Authors:  M Sekine; K Sasahara; T Kojima; T Morioka
Journal:  Antimicrob Agents Chemother       Date:  1982-05       Impact factor: 5.191

5.  Absorption and disposition of ampicillin in the elderly.

Authors:  E J Triggs; J M Johnson; B Learoyd
Journal:  Eur J Clin Pharmacol       Date:  1980-08       Impact factor: 2.953

  5 in total

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