Literature DB >> 8392712

A novel method to stabilise antisense oligonucleotides against exonuclease degradation.

I M Khan1, J M Coulson.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8392712      PMCID： PMC309707          DOI： 10.1093/nar/21.12.2957

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


× No keyword cloud information.
  8 in total

1.  Antisense oligonucleotides as antiviral agents.

Authors:  J Coulson; A D Malcolm
Journal:  Ann N Y Acad Sci       Date:  1992-10-28       Impact factor: 5.691

2.  The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts.

Authors:  B C Chu; L E Orgel
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

3.  Modified deoxyoligonucleotides stable to exonuclease degradation in serum.

Authors:  J P Shaw; K Kent; J Bird; J Fishback; B Froehler
Journal:  Nucleic Acids Res       Date:  1991-02-25       Impact factor: 16.971

4.  Extraordinary stable structure of short single-stranded DNA fragments containing a specific base sequence: d(GCGAAAGC).

Authors:  I Hirao; Y Nishimura; T Naraoka; K Watanabe; Y Arata; K Miura
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971

5.  Oligodeoxynucleotide folding in solution: loop size and stability of B-hairpins.

Authors:  L E Xodo; G Manzini; F Quadrifoglio; G A van der Marel; J H van Boom
Journal:  Biochemistry       Date:  1988-08-23       Impact factor: 3.162

6.  Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at near-physiological conditions.

Authors:  S Young; R W Wagner
Journal:  Nucleic Acids Res       Date:  1991-05-11       Impact factor: 16.971

7.  Substrate specificity and kinetics of degradation of antisense oligonucleotides by a 3' exonuclease in plasma.

Authors:  P S Eder; R J DeVine; J M Dagle; J A Walder
Journal:  Antisense Res Dev       Date:  1991

8.  Oligodeoxynucleotide stability in subcellular extracts and culture media.

Authors:  E Wickstrom
Journal:  J Biochem Biophys Methods       Date:  1986-09
  8 in total
  13 in total

1.  Diversity-oriented solid-phase synthesis and biological evaluation of oligonucleotide hairpins as HIV-1 RT RNase H inhibitors.

Authors:  Rami N Hannoush; Kyung-Lyum Min; Masad J Damha
Journal:  Nucleic Acids Res       Date:  2004-11-29       Impact factor: 16.971

Review 2.  Application of antisense DNA method for the study of molecular bases of brain function and behavior.

Authors:  S Ogawa; D W Pfaff
Journal:  Behav Genet       Date:  1996-05       Impact factor: 2.805

3.  Opening of the extraordinarily stable mini-hairpin d(GCGAAGC).

Authors:  B Jollès; M Réfrégiers; A Laigle
Journal:  Nucleic Acids Res       Date:  1997-11-15       Impact factor: 16.971

4.  Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.

Authors:  M Pantaleon; M B Harvey; W S Pascoe; D E James; P L Kaye
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

5.  Most compact hairpin-turn structure exerted by a short DNA fragment, d(GCGAAGC) in solution: an extraordinarily stable structure resistant to nucleases and heat.

Authors:  I Hirao; G Kawai; S Yoshizawa; Y Nishimura; Y Ishido; K Watanabe; K Miura
Journal:  Nucleic Acids Res       Date:  1994-02-25       Impact factor: 16.971

6.  Influence of the nature of the porphyrin ligand on the nuclease activity of metalloporphyrin-oligonucleotide conjugates designed with cationic, hydrophobic or anionic metalloporphyrins.

Authors:  B Mestre; M Pitié; C Loup; C Claparols; G Pratviel; B Meunier
Journal:  Nucleic Acids Res       Date:  1997-03-01       Impact factor: 16.971

7.  Nuclease resistance of an extraordinarily thermostable mini-hairpin DNA fragment, d(GCGAAGC) and its application to in vitro protein synthesis.

Authors:  S Yoshizawa; T Ueda; Y Ishido; K Miura; K Watanabe; I Hirao
Journal:  Nucleic Acids Res       Date:  1994-06-25       Impact factor: 16.971

8.  K+ channel antisense oligodeoxynucleotides inhibit cytokine-induced expansion of human hemopoietic progenitors.

Authors:  O Shirihai; S Merchav; B Attali; D Dagan
Journal:  Pflugers Arch       Date:  1996-02       Impact factor: 3.657

9.  A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification.

Authors:  Ming Jiang; Andrey A Arzumanov; Michael J Gait; Jo Milner
Journal:  Nucleic Acids Res       Date:  2005-10-07       Impact factor: 16.971

10.  RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3' Nuclease-resistant Mini-hairpin Structure.

Authors:  Simon J Allison; Jo Milner
Journal:  Mol Ther Nucleic Acids       Date:  2014-01-07       Impact factor: 10.183
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.