Literature DB >> 8392185

Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro.

Y K Shimizu1, R H Purcell, H Yoshikura.   

Abstract

A murine retrovirus-infected human T-cell line, HPB-Ma, supported replication of hepatitis C virus (HCV) at least as well as the previously reported Molt4-Ma cells. Cloning of HPB-Ma cells revealed a clonal variation of cellular susceptibility to HCV infection. Using one of the sensitive clones, we tested HCV inocula from different sources for their infectivity titer in cell culture. The in vitro titers obtained correlated with the reported infectivity titers of the inocula in chimpanzees. Thus, the system appears to be useful for estimating the in vivo infectivity of HCV.

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Year:  1993        PMID： 8392185      PMCID： PMC46862          DOI： 10.1073/pnas.90.13.6037

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome.

Authors:  Q L Choo; G Kuo; A J Weiner; L R Overby; D W Bradley; M Houghton
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

Review 2.  Hepatitis C virus: the major causative agent of viral non-A, non-B hepatitis.

Authors:  Q L Choo; A J Weiner; L R Overby; G Kuo; M Houghton; D W Bradley
Journal:  Br Med Bull       Date:  1990-04       Impact factor: 4.291

3.  Effect of cycloheximide on RNA metabolism early in productive infection with adenovirus 2.

Authors:  E A Craig; H J Raskas
Journal:  J Virol       Date:  1974-07       Impact factor: 5.103

4.  Inhibition of human immunodeficiency virus (HIV-1) replication by synthetic oligo-RNA derivatives.

Authors:  S Shibahara; S Mukai; H Morisawa; H Nakashima; S Kobayashi; N Yamamoto
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

5.  Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

Authors:  N Kato; M Hijikata; Y Ootsuyama; M Nakagawa; S Ohkoshi; T Sugimura; K Shimotohno
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

6.  Induction of type-C RNA virus by cycloheximide: increased expression of virus-specific RNA.

Authors:  S A Aaronson; G R Anderson; C Y Dunn; K C Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205

7.  Non-A, non-B hepatitis in chimpanzees and marmosets.

Authors:  S M Feinstone; H J Alter; H P Dienes; Y Shimizu; H Popper; D Blackmore; D Sly; W T London; R H Purcell
Journal:  J Infect Dis       Date:  1981-12       Impact factor: 5.226

8.  An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

Authors:  G Kuo; Q L Choo; H J Alter; G L Gitnick; A G Redeker; R H Purcell; T Miyamura; J L Dienstag; M J Alter; C E Stevens
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

9.  Transmissible agent in non-A, non-B hepatitis.

Authors:  H J Alter; R H Purcell; P V Holland; H Popper
Journal:  Lancet       Date:  1978-03-04       Impact factor: 79.321

10.  Thermostability of human immunodeficiency virus (HIV-1) in a liquid matrix is far higher than that of an ecotropic murine leukemia virus.

Authors:  H Yoshikura
Journal:  Jpn J Cancer Res       Date:  1989-01
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  34 in total

1.  Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees.

Authors:  Y K Shimizu; H Igarashi; T Kanematu; K Fujiwara; D C Wong; R H Purcell; H Yoshikura
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

2.  Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor.

Authors:  S Wünschmann; J D Medh; D Klinzmann; W N Schmidt; J T Stapleton
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

3.  Transfection of HepG2 cells with infectious hepatitis C virus genome.

Authors:  S Dash; A B Halim; H Tsuji; N Hiramatsu; M A Gerber
Journal:  Am J Pathol       Date:  1997-08       Impact factor: 4.307

Review 4.  Economics of pathogen inactivation technology for platelet concentrates in Japan.

Authors:  Ulf Staginnus; Laurence Corash
Journal:  Int J Hematol       Date:  2004-11       Impact factor: 2.490

Review 5.  Cell culture systems for the hepatitis C virus.

Authors:  Gilles Duverlie; Czeslaw Wychowski
Journal:  World J Gastroenterol       Date:  2007-05-07       Impact factor: 5.742

6.  Functional role of hepatitis C virus chimeric glycoproteins in the infectivity of pseudotyped virus.

Authors:  L M Lagging; K Meyer; R J Owens; R Ray
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

7.  Use of whole blood specimens for routine clinical quantitation of hepatitis C virus RNA does not increase assay sensitivity.

Authors:  L Cook; A M Ross; G B Knight; V Agnello
Journal:  J Clin Microbiol       Date:  2000-12       Impact factor: 5.948

8.  Multicycle infection of hepatitis C virus in cell culture and inhibition by alpha and beta interferons.

Authors:  Y K Shimizu; H Yoshikura
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

9.  The native form and maturation process of hepatitis C virus core protein.

Authors:  K Yasui; T Wakita; K Tsukiyama-Kohara; S I Funahashi; M Ichikawa; T Kajita; D Moradpour; J R Wands; M Kohara
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

10.  Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA.

Authors:  A A Kolykhalov; S M Feinstone; C M Rice
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103
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