Literature DB >> 7966635

Multicycle infection of hepatitis C virus in cell culture and inhibition by alpha and beta interferons.

Y K Shimizu1, H Yoshikura.   

Abstract

We previously reported that a clone of a human lymphocytic cell line, HPBMa clone 10-2, supports the genome replication of hepatitis C virus (HCV). In the present study, the multicycle transmission of HCV from infected cells to new cells was demonstrated by coculture with drug-resistant cells as recipients; i.e., the system was proved productive for infectious HCV. Inhibition of viral replication by alpha and beta interferons was observed.

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Year:  1994        PMID： 7966635      PMCID： PMC237312          DOI： 10.1128/JVI.68.12.8406-8408.1994

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  8 in total

1.  Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Authors:  P J Southern; P Berg
Journal:  J Mol Appl Genet       Date:  1982

2.  Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial.

Authors:  A M Di Bisceglie; P Martin; C Kassianides; M Lisker-Melman; L Murray; J Waggoner; Z Goodman; S M Banks; J H Hoofnagle
Journal:  N Engl J Med       Date:  1989-11-30       Impact factor: 91.245

3.  Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro.

Authors:  Y K Shimizu; R H Purcell; H Yoshikura
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

4.  Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.

Authors:  M Hijikata; Y K Shimizu; H Kato; A Iwamoto; J W Shih; H J Alter; R H Purcell; H Yoshikura
Journal:  J Virol       Date:  1993-04       Impact factor: 5.103

5.  Mulcos: a vector for amplification and simultaneous expression of two foreign genes in mammalian cells.

Authors:  H Ikeda; J Trowsdale; I Saito
Journal:  Gene       Date:  1988-11-15       Impact factor: 3.688

6.  Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line.

Authors:  Y K Shimizu; A Iwamoto; M Hijikata; R H Purcell; H Yoshikura
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

7.  Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses.

Authors:  Y K Shimizu; M Hijikata; A Iwamoto; H J Alter; R H Purcell; H Yoshikura
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

8.  Thermostability of human immunodeficiency virus (HIV-1) in a liquid matrix is far higher than that of an ecotropic murine leukemia virus.

Authors:  H Yoshikura
Journal:  Jpn J Cancer Res       Date:  1989-01
  8 in total
  7 in total

Review 1.  Hepatitis C virus: molecular biology and genetic variability.

Authors:  C Bréchot
Journal:  Dig Dis Sci       Date:  1996-12       Impact factor: 3.199

2.  Cell type-specific enhancement of hepatitis C virus internal ribosome entry site-directed translation due to 5' nontranslated region substitutions selected during passage of virus in lymphoblastoid cells.

Authors:  H Lerat; Y K Shimizu; S M Lemon
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

3.  Alpha interferon inhibits hepatitis C virus replication in primary human hepatocytes infected in vitro.

Authors:  Valérie Castet; Chantal Fournier; Alexandre Soulier; Rozenn Brillet; Joliette Coste; Dominique Larrey; Daniel Dhumeaux; Patrick Maurel; Jean-Michel Pawlotsky
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

4.  Characterization of long-term cultures of hepatitis C virus.

Authors:  N Nakajima; M Hijikata; H Yoshikura; Y K Shimizu
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

5.  Characterization of hepatitis C virus replication in cloned cells obtained from a human T-cell leukemia virus type 1-infected cell line, MT-2.

Authors:  T Mizutani; N Kato; S Saito; M Ikeda; K Sugiyama; K Shimotohno
Journal:  J Virol       Date:  1996-10       Impact factor: 5.103

6.  Biological significance of HCV in various kinds of lymphoid cells.

Authors:  Yasuteru Kondo; Yoshiyuki Ueno; Tooru Shimosegawa
Journal:  Int J Microbiol       Date:  2012-02-22

Review 7.  Virology of hepatitis C virus.

Authors:  P Simmonds
Journal:  Clin Ther       Date:  1996       Impact factor: 3.393
  7 in total

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