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Literature DB >> 8387172

Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.

Abstract

We purified and sequenced from bovine brain a novel calcium-binding protein. This protein which we named neurocalcin has 3 putative EF hand motifs and a close homology with recoverin which activates guanylate cyclase Ca2+ dependently. Neurocalcin has at least 6 isoforms and is expressed in the central nervous system (CNS), retina and adrenal gland. Considering unique distribution of neurocalcin, this protein may an important physiological role which differs from that of visinin or recoverin.

Entities: Chemical Gene Species

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Year: 1993 PMID： 8387172 DOI： 10.1016/0168-0102(93)90074-z

Source DB: PubMed Journal: Neurosci Res ISSN： 0168-0102 Impact factor: 3.304

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Cited

16 in total

1. Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies.

Authors: I Sokal; N Li; C S Klug; S Filipek; W L Hubbell; W Baehr; K Palczewski
Journal: J Biol Chem Date: 2001-08-27 Impact factor: 5.157

2. Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.

Authors: Masumi Kamiyama; Masaaki Kobayashi; Shin-ichi Araki; Aritoshi Iida; Tatsuhiko Tsunoda; Koichi Kawai; Masahito Imanishi; Makoto Nomura; Tetsuya Babazono; Yasuhiko Iwamoto; Atsunori Kashiwagi; Kohei Kaku; Ryuzou Kawamori; Daniel P K Ng; Torben Hansen; Peter Gaede; Oluf Pedersen; Yusuke Nakamura; Shiro Maeda
Journal: Hum Genet Date: 2007-08-02 Impact factor: 4.132

3. Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality.

Authors: Mitsuhiko Ikura; James B Ames
Journal: Proc Natl Acad Sci U S A Date: 2006-01-23 Impact factor: 11.205

4. Structure of a Ca2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast.

Authors: Sunghyuk Lim; Thomas Strahl; Jeremy Thorner; James B Ames
Journal: J Biol Chem Date: 2011-02-02 Impact factor: 5.157

5. The effect of recombinant recoverin on the photoresponse of truncated rod photoreceptors.

Authors: M A Erickson; L Lagnado; S Zozulya; T A Neubert; L Stryer; D A Baylor
Journal: Proc Natl Acad Sci U S A Date: 1998-05-26 Impact factor: 11.205

6. Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis.

Authors: Markus Riessland; Anna Kaczmarek; Svenja Schneider; Kathryn J Swoboda; Heiko Löhr; Cathleen Bradler; Vanessa Grysko; Maria Dimitriadi; Seyyedmohsen Hosseinibarkooie; Laura Torres-Benito; Miriam Peters; Aaradhita Upadhyay; Nasim Biglari; Sandra Kröber; Irmgard Hölker; Lutz Garbes; Christian Gilissen; Alexander Hoischen; Gudrun Nürnberg; Peter Nürnberg; Michael Walter; Frank Rigo; C Frank Bennett; Min Jeong Kye; Anne C Hart; Matthias Hammerschmidt; Peter Kloppenburg; Brunhilde Wirth
Journal: Am J Hum Genet Date: 2017-01-26 Impact factor: 11.025

Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.

1. Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies.

2. Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.

3. Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality.

4. Structure of a Ca2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast.

5. The effect of recombinant recoverin on the photoresponse of truncated rod photoreceptors.

6. Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis.

7. S100 beta is a target protein of neurocalcin delta, an abundant isoform in glial cells.

Review 8. Molecular structure and target recognition of neuronal calcium sensor proteins.

9. Neuronal calcium sensor-1 (Ncs1p) is up-regulated by calcineurin to promote Ca2+ tolerance in fission yeast.

10. (1)H, (15)N, and (13)C chemical shift assignments of neuronal calcium sensor-1 homolog from fission yeast.