Literature DB >> 8386834

A very poorly expressed tRNA(Ser) is highly concentrated together with replication primer initiator tRNA(Met) in the yeast Ty1 virus-like particles.

P Pochart1, B Agoutin, C Fix, G Keith, T Heyman.   

Abstract

The analysis of the tRNAs associated to the virus-like particles produced by the Ty1 element revealed the specific packaging of three major tRNA species, in about equal amounts: the replication primer initiator tRNA(Met), the tRNA(Ser)AGA and a tRNA undetected until now as an expressed species in yeast. The latter tRNA is coded by the already described tDNA(Ser)GCT. This tRNA is enriched more than 150 fold in the particles as compared to its content in total cellular tRNA where it represents less than 0.1% (initiator tRNA(Met) and tRNA(Ser)AGA being 11 and 4 fold enriched respectively). This tRNA is the only species coded by the tDNA(Ser)GCT gene which is found in three copies per genome since no other corresponding expressed tRNA could be detected. This gene is thus very poorly expressed. The high concentration of tRNA(Ser)GCU in the particles compared to its very low cellular content led us to consider its possible implication in Ty specific processes.

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Year:  1993        PMID： 8386834      PMCID： PMC309356          DOI： 10.1093/nar/21.7.1517

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  23 in total

1.  Ty elements transpose through an RNA intermediate.

Authors:  J D Boeke; D J Garfinkel; C A Styles; G R Fink
Journal:  Cell       Date:  1985-03       Impact factor: 41.582

2.  The methionine initiator tRNA genes of yeast.

Authors:  A M Cigan; T F Donahue
Journal:  Gene       Date:  1986       Impact factor: 3.688

3.  Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase.

Authors:  S Goff; P Traktman; D Baltimore
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

4.  [Fractionation of Brewer's yeast t-RNA by countercurrent distribution].

Authors:  G Dirheimer; J P Ebel
Journal:  Bull Soc Chim Biol (Paris)       Date:  1967

5.  Characterization of the yeast mobile element Ty1.

Authors:  H Eibel; J Gafner; A Stotz; P Philippsen
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1981

6.  Correlation between the abundance of yeast transfer RNAs and the occurrence of the respective codons in protein genes. Differences in synonymous codon choice patterns of yeast and Escherichia coli with reference to the abundance of isoaccepting transfer RNAs.

Authors:  T Ikemura
Journal:  J Mol Biol       Date:  1982-07-15       Impact factor: 5.469

7.  Processing of TY1 proteins and formation of Ty1 virus-like particles in Saccharomyces cerevisiae.

Authors:  F Müller; K H Brühl; K Freidel; K V Kowallik; M Ciriacy
Journal:  Mol Gen Genet       Date:  1987-05

8.  Polyacrylamide gel mapping of chicken tRNA: comparison of polysome-bound and whole-cell tRNA from normal and avian sarcoma virus-infected chicken embryo fibroblasts.

Authors:  F Reinisch; T Heyman
Journal:  Mol Cell Biol       Date:  1982-10       Impact factor: 4.272

9.  Nickel-specific T lymphocyte clones derived from allergic nickel-contact dermatitis lesions in man: heterogeneity based on requirement of dendritic antigen-presenting cell subsets.

Authors:  M L Kapsenberg; P Res; J D Bos; A Schootemijer; M B Teunissen; W Van Schooten
Journal:  Eur J Immunol       Date:  1987-06       Impact factor: 5.532

10.  Initiator methionine tRNA is essential for Ty1 transposition in yeast.

Authors:  K B Chapman; A S Byström; J D Boeke
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205
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  6 in total

1.  Multiple molecular determinants for retrotransposition in a primer tRNA.

Authors:  J B Keeney; K B Chapman; V Lauermann; D F Voytas; S U Aström; U von Pawel-Rammingen; A Byström; J D Boeke
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272

2.  In vivo Ty1 reverse transcription can generate replication intermediates with untidy ends.

Authors:  E H Mules; O Uzun; A Gabriel
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

3.  Extended interactions between the primer tRNAi(Met) and genomic RNA of the yeast Ty1 retrotransposon.

Authors:  S Friant; T Heyman; M L Wilhelm; F X Wilhelm
Journal:  Nucleic Acids Res       Date:  1996-02-01       Impact factor: 16.971

4.  Interactions between Ty1 retrotransposon RNA and the T and D regions of the tRNA(iMet) primer are required for initiation of reverse transcription in vivo.

Authors:  S Friant; T Heyman; A S Byström; M Wilhelm; F X Wilhelm
Journal:  Mol Cell Biol       Date:  1998-02       Impact factor: 4.272

5.  Biochemical and electron microscope analyses of the DNA reverse transcripts present in the virus-like particles of the yeast transposon Ty1. Identification of a second origin of Ty1DNA plus strand synthesis.

Authors:  P Pochart; B Agoutin; S Rousset; R Chanet; V Doroszkiewicz; T Heyman
Journal:  Nucleic Acids Res       Date:  1993-07-25       Impact factor: 16.971

6.  Yeast Ty1 retrotransposon: the minus-strand primer binding site and a cis-acting domain of the Ty1 RNA are both important for packaging of primer tRNA inside virus-like particles.

Authors:  M Wilhelm; F X Wilhelm; G Keith; B Agoutin; T Heyman
Journal:  Nucleic Acids Res       Date:  1994-11-11       Impact factor: 16.971
  6 in total

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