Literature DB >> 8385635

Superoxide radical scavenging activity of phenolic compounds.

Y Tsujimoto1, H Hashizume, M Yamazaki.   

Abstract

1. Superoxide radicals (O2-.) were generated from a hypoxanthin-xanthin oxidase (HPX-XOD) reaction system and detected by the electron spin resonance (ESR) spin-trapping technique. 2. The inhibitory effect on O2-. generation occurred in the order: superoxide dismutase (SOD) > L-ascorbic acid > eugenol > guaiacol > phenol. 3. And the second-order rate constants between O2-. and samples were: SOD 1.7 x 10(9)/M/S, L-ascorbic acid 3.4 x 10(5)/M/S, eugenol 8.3 x 10(3)/M/S, guaiacol 2.5 x 10(3)/M/S and phenol 5.8 x 10(2)/M/S. 4. It was clarified that the phenolic compounds have O2-. scavenging activity.

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Year:  1993        PMID： 8385635     DOI： 10.1016/0020-711x(93)90655-x

Source DB:  PubMed          Journal:  Int J Biochem        ISSN： 0020-711X


  6 in total

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  6 in total

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