STUDY OBJECTIVES: To test whether buffered lidocaine is less painful to administer as a digital nerve block than plain lidocaine. DESIGN: Randomized, double-blind, prospective clinical trial. SETTING:University hospital emergency department. PARTICIPANTS: Adults not allergic to lidocaine requiring a digital nerve block. INTERVENTIONS: Subjects received digital nerve blocks by injection of buffered lidocaine on one side and plain lidocaine on the other in a predetermined, randomized order. Pain of infiltration was assessed. Scores were compared using a two-tailed t-test. Standard 1% lidocaine was used if additional anesthetic was required. MEASUREMENTS AND MAIN RESULTS:Thirty-one patients were enrolled. Buffered lidocaine was significantly less painful to administer than plain lidocaine (P < .001; t = 4.21). Supplemental anesthesia was required less often for buffered lidocaine (two times) compared with plain lidocaine (six times), although this difference was not statistically significant. CONCLUSION: Because it causes less pain and is equally efficacious, buffered lidocaine is preferable to plain lidocaine for digital nerve blocks in adults.
RCT Entities:
STUDY OBJECTIVES: To test whether buffered lidocaine is less painful to administer as a digital nerve block than plain lidocaine. DESIGN: Randomized, double-blind, prospective clinical trial. SETTING: University hospital emergency department. PARTICIPANTS: Adults not allergic to lidocaine requiring a digital nerve block. INTERVENTIONS: Subjects received digital nerve blocks by injection of buffered lidocaine on one side and plain lidocaine on the other in a predetermined, randomized order. Pain of infiltration was assessed. Scores were compared using a two-tailed t-test. Standard 1% lidocaine was used if additional anesthetic was required. MEASUREMENTS AND MAIN RESULTS: Thirty-one patients were enrolled. Buffered lidocaine was significantly less painful to administer than plain lidocaine (P < .001; t = 4.21). Supplemental anesthesia was required less often for buffered lidocaine (two times) compared with plain lidocaine (six times), although this difference was not statistically significant. CONCLUSION: Because it causes less pain and is equally efficacious, buffered lidocaine is preferable to plain lidocaine for digital nerve blocks in adults.
Authors: Tiffany Y Borbón; Pingping Qu; T Tausala Coleman-Satterfield; Ryan Kearney; Eileen J Klein Journal: J Am Coll Emerg Physicians Open Date: 2022-07-01
Authors: Bhakti K Patel; Blair N Wendlandt; Krysta S Wolfe; Shruti B Patel; Elizabeth R Doman; Anne S Pohlman; Jesse B Hall; John P Kress Journal: Chest Date: 2018-04-24 Impact factor: 9.410