Literature DB >> 8380614

A remarkable change of opioid receptor selectivity on the attachment of a peptidomimetic kappa address element to the delta antagonist, natrindole: 5'-[N2-alkylamidino)methyl]naltrindole derivatives as a novel class of kappa opioid receptor antagonists.

S L Olmsted1, A E Takemori, P S Portoghese.   

Abstract

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Year:  1993        PMID： 8380614     DOI： 10.1021/jm00053a025

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  8 in total

Review 1.  Kappa opioid antagonists: past successes and future prospects.

Authors:  Matthew D Metcalf; Andrew Coop
Journal:  AAPS J       Date:  2005-10-27       Impact factor: 4.009

2.  Application of the message-address concept to the docking of naltrexone and selective naltrexone-derived opioid antagonists into opioid receptor models.

Authors:  T G Metzger; M G Paterlini; P S Portoghese; D M Ferguson
Journal:  Neurochem Res       Date:  1996-11       Impact factor: 3.996

Review 3.  Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuse.

Authors:  Thomas E Prisinzano
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

4.  Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships.

Authors:  Peter L Katavic; Kenneth Lamb; Hernan Navarro; Thomas E Prisinzano
Journal:  J Nat Prod       Date:  2007-08-09       Impact factor: 4.050

5.  In vivo and in vitro characterization of naltrindole-derived ligands at the κ-opioid receptor.

Authors:  Joseph J Casal-Dominguez; Mary Clark; John R Traynor; Stephen M Husbands; Sarah J Bailey
Journal:  J Psychopharmacol       Date:  2012-10-31       Impact factor: 4.153

6.  Probing ligand recognition of the opioid pan antagonist AT-076 at nociceptin, kappa, mu, and delta opioid receptors through structure-activity relationships.

Authors:  V Blair Journigan; Willma E Polgar; Edward W Tuan; James Lu; Pankaj R Daga; Nurulain T Zaveri
Journal:  Sci Rep       Date:  2017-10-16       Impact factor: 4.379

Review 7.  Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?

Authors:  Sarah J Bailey; Stephen M Husbands
Journal:  Neuronal Signal       Date:  2018-05-14

8.  Molecular switches of the κ opioid receptor triggered by 6'-GNTI and 5'-GNTI.

Authors:  Jianxin Cheng; Xianqiang Sun; Weihua Li; Guixia Liu; Yaoquan Tu; Yun Tang
Journal:  Sci Rep       Date:  2016-01-08       Impact factor: 4.379
  8 in total

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