| Literature DB >> 8376519 |
M I Múnera-Jaramillo1, S Botero-Garcés.
Abstract
A high-performance liquid chromatographic technique with a lower detection limit for measuring tenoxicam plasma levels was standardized. Tenoxicam was extracted with dichloromethane from acidified plasma and the evaporated extracts were analysed on a reversed-phase column using a methanol-phosphate buffer mobile phase and setting ultraviolet detection at 355 nm. A reproducible calibration curve in the 5-2000 ng/ml range was obtained. The mean recovery of extraction was 98.99 +/- 4.3% and the detection limit was 5 ng/ml.Entities:
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Year: 1993 PMID: 8376519 DOI: 10.1016/0378-4347(93)80407-u
Source DB: PubMed Journal: J Chromatogr