Literature DB >> 8371784

[Importance of cell self-organization for tumor biology].

B Wolf1, M Kraus.   

Abstract

A cell is a complex system working far from thermodynamic equilibrium. The prediction of cellular functions based exclusively on the molecular basis is yet impossible because of the many degrees of freedom of the microsystem cell. In contrast, the system cell displays only a surprisingly small spectrum of macroscopic observable degrees of freedom, the number of which changes during the cell cycle and neoplastic growth. Illustrated by image analytical and cell biological data we attempt to describe these phenomena of cellular self-organization.

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Mesh:

Year:  1993        PMID: 8371784     DOI: 10.1007/bf01138789

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  54 in total

1.  A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase.

Authors:  A Goldbeter
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

2.  Preliminary investigations of a correlation between electron energy loss and morphometric analyses on ultrathin cryosections from normal and neoplastic gastric tissues.

Authors:  B Wolf; E Bischoff; A Schwinde
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

Review 3.  The molecular heterogeneity of protein kinase C and its implications for cellular regulation.

Authors:  Y Nishizuka
Journal:  Nature       Date:  1988-08-25       Impact factor: 49.962

4.  Ultrastructural morphometric studies on benign and malignant lung tumours.

Authors:  B Wolf; C Lezius; A Schwinde
Journal:  Anticancer Res       Date:  1987 May-Jun       Impact factor: 2.480

5.  Changes of free calcium levels with stages of the cell division cycle.

Authors:  M Poenie; J Alderton; R Y Tsien; R A Steinhardt
Journal:  Nature       Date:  1985 May 9-15       Impact factor: 49.962

6.  Requirement of the Na+/H+ exchanger for tumor growth.

Authors:  D Rotin; D Steele-Norwood; S Grinstein; I Tannock
Journal:  Cancer Res       Date:  1989-01-01       Impact factor: 12.701

7.  Topography and numerical densities of intramembrane particles in chemical carcinogen-induced urinary bladder carcinomas in Fischer rats.

Authors:  B U Pauli; G H Friedell; R S Weinstein
Journal:  Lab Invest       Date:  1978-12       Impact factor: 5.662

8.  Carcinoembryonic antigen functions as an accessory adhesion molecule mediating colon epithelial cell-collagen interactions.

Authors:  M Pignatelli; H Durbin; W F Bodmer
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

Review 9.  Activated oncogenes in human tumors.

Authors:  H G Suárez
Journal:  Anticancer Res       Date:  1989 Sep-Oct       Impact factor: 2.480

10.  Tumor cell invasion of three-dimensional matrices of defined composition: evidence for a specific role for heparan sulfate in rodent cell lines.

Authors:  N P Robertson; J R Starkey; S Hamner; G G Meadows
Journal:  Cancer Res       Date:  1989-04-01       Impact factor: 12.701

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