Literature DB >> 837004

The effect of non-steroidal anti-inflammatory drugs on adenosine triphosphate content and histamine release from rat peritoneal cell suspensions rich in mast cells.

G D Champion, R O Day, J E Ray, D N Wade.   

Abstract

1 Non-steroidal anti-inflammatory drugs (NSAID) suppressed compound 48/80-induced histamine release from rat peritoneal cells in vitro in a dose-dependent manner. 2 NSAID suppressed the adenosine triphosphate (ATP) content of rat peritoneal cells in vitro and this correlated strongly with the suppression of compound 48/80-induced histamine release. 3 The correlation demonstrated suggests that the mechanism of action of NSAID in the rat peritoneal cells is via depletion of cellular ATP.

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Year:  1977        PMID： 837004      PMCID： PMC1667715          DOI： 10.1111/j.1476-5381.1977.tb06973.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  34 in total

1.  BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS--III. UNCOUPLING OF OXIDATIVE PHOSPHORYLATION IN A CONNECTIVE TISSUE (CARTILAGE) AND LIVER MITOCHONDRIA BY SALICYLATE ANALOGUES: RELATIONSHIP OF STRUCTURE TO ACTIVITY.

Authors:  M W WHITEHOUSE
Journal:  Biochem Pharmacol       Date:  1964-03       Impact factor: 5.858

2.  Mechanism of histamine release in mast cells.

Authors:  B UVNAS
Journal:  Ann N Y Acad Sci       Date:  1963-02-26       Impact factor: 5.691

3.  Evidence for energy-requiring processes in histamine release and mast cell degranulation in rat tissues induced by compound 48/80.

Authors:  B DIAMANT; B UVNAS
Journal:  Acta Physiol Scand       Date:  1961 Nov-Dec

4.  A procedure for the determination of histamine.

Authors:  L T KREMZNER; I B WILSON
Journal:  Biochim Biophys Acta       Date:  1961-06-24

5.  A method for the fluorometric assay of histamine in tissues.

Authors:  P A SHORE; A BURKHALTER; V H COHN
Journal:  J Pharmacol Exp Ther       Date:  1959-11       Impact factor: 4.030

6.  Inhibition of the anaphylactic reaction.

Authors:  J L MONGAR; H O SCHILD
Journal:  J Physiol       Date:  1957-02-15       Impact factor: 5.182

7.  Cellular mechanisms in anaphylaxis.

Authors:  J L MONGAR; H O SCHILD
Journal:  Physiol Rev       Date:  1962-04       Impact factor: 37.312

8.  The effect of anti-inflammatory drugs on increased vascular permeability induced by chemical mediators.

Authors:  J Carr
Journal:  J Pathol       Date:  1972-09       Impact factor: 7.996

9.  Dependence of histamine release from rat mast cells on adenosine triphosphate.

Authors:  T Johansen; N Chakravarty
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

10.  The role of the alkaline earth ions in anaphylactic histamine secretion.

Authors:  J C Foreman; J L Mongar
Journal:  J Physiol       Date:  1972-08       Impact factor: 5.182
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  3 in total

1.  Comparative studies on the effect of non-steroidal anti-inflammatory drugs (NSAID) on histamine release from mast cells of the rat and guinea pig.

Authors:  J C Gomes; F L Pearce
Journal:  Agents Actions       Date:  1988-07

2.  Effect of arachidonic acid metabolism on the release of histamine and SRS (leukotrienes) from guinea-pig lung.

Authors:  N Chakravarty
Journal:  Agents Actions       Date:  1984-04

3.  The measurement of histamine release from suspensions of rat peritoneal cells rich in mast cells.

Authors:  R O Day; P D Paull; J E Ray; D N Wade
Journal:  Agents Actions       Date:  1977-10
  3 in total

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