Literature DB >> 8369997

Correlation between densitometric and hystomorphometric values in isolated vertebrae of Sprague-Dawley rats.

I Campodarve1, A Diez, J Puig, S Serrano, M L Mariñoso, M D Arnau, J Cucurull, J Ibáñez, X Nogués, J Aubia.   

Abstract

The study of bone mass in experimental animals usually requires invasive techniques. Dual energy X-ray absorptiometry (DEXA) may be an alternative as a non-invasive method (1). Bone mineral density (BMD) and bone mineral content (BMC) of 62 vertebrae of Sprague Dawley rats (SDr) measured by DEXA densitometry were compared with histomorphometric bone volume measurements, and a statistically significant correlation was found (r = 0.79 and 0.75, respectively, p < 0.001). In conclusion, DEXA is an accurate and feasible technique for the study of trabecular bone mass in SDr.

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Year:  1993        PMID: 8369997     DOI: 10.1007/bf00571339

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN: 0171-967X            Impact factor:   4.333


  3 in total

1.  Sequential and precise in vivo measurement of bone mineral density in rats using dual-energy x-ray absorptiometry.

Authors:  P Ammann; R Rizzoli; D Slosman; J P Bonjour
Journal:  J Bone Miner Res       Date:  1992-03       Impact factor: 6.741

Review 2.  Current and innovative methods for noninvasive bone densitometry.

Authors:  D J Sartoris; D Resnick
Journal:  Radiol Clin North Am       Date:  1990-03       Impact factor: 2.303

3.  The rat as an animal model for the study of senile idiopathic osteoporosis.

Authors:  M R Simon
Journal:  Acta Anat (Basel)       Date:  1984
  3 in total
  1 in total

1.  Specific evaluation of localized bone mass and bone loss in the rat using dual-energy X-ray absorptiometry subregional analysis.

Authors:  P Pastoureau; A Chomel; J Bonnet
Journal:  Osteoporos Int       Date:  1995-05       Impact factor: 4.507

  1 in total

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