Literature DB >> 8359852

Inhibition of lipid peroxidation by piperine during experimental inflammation in rats.

J N Dhuley1, P H Raman, A M Mujumdar, S R Naik.   

Abstract

Carrageenin induced rat paw oedema shows a direct co-relationship with liver lipid peroxidation and not with kidney or brain. Pretreatment with piperine or oxyphenylbutazone reduced the liver lipid peroxidation, acid phosphatase and oedema induced by carrageenin. However, no such co-relationship was observed with treatment of these anti-inflammatory agents in control animals. It is, therefore, suggested that the inhibition of these liver enzymes is non specific in nature.

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Year:  1993        PMID: 8359852

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  5 in total

1.  A role of piperine on monosodium urate crystal-induced inflammation--an experimental model of gouty arthritis.

Authors:  Evan Prince Sabina; Shruthi Nagar; Mahaboobkhan Rasool
Journal:  Inflammation       Date:  2011-06       Impact factor: 4.092

2.  Studies on effect of piperine on oral bioavailability of ampicillin and norfloxacin.

Authors:  Kunchithapatham Janakiraman; Rajappan Manavalan
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-04-10

3.  Studies on the neuroprotective role of Piper longum in C6 glioma induced rats.

Authors:  Umadevi Subramanian; Sharmila Poongavanam; A J Vanisree
Journal:  Invest New Drugs       Date:  2010-10       Impact factor: 3.850

4.  Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway.

Authors:  Yi Lin; Jianping Xu; Hehe Liao; Lu Li; Lei Pan
Journal:  Tumour Biol       Date:  2013-11-24

5.  White pepper and piperine have different effects on pharmacokinetics of puerarin in rats.

Authors:  Yong-Zhuo Liang; Hai-Ming Chen; Zu-Qing Su; Shao-Zhen Hou; Xiao-Ying Chen; Yi-Feng Zheng; Yu-Cui Li; Ji Lin; Janis Ya-Xian Zhan; Zi-Ren Su; Lu-Di Fu
Journal:  Evid Based Complement Alternat Med       Date:  2014-06-01       Impact factor: 2.629

  5 in total

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