Literature DB >> 8350417

Detection of Leishmania RNA virus 1 proteins.

T L Cadd1, M C Keenan, J L Patterson.   

Abstract

Polyclonal antiserum was raised against the peak viral fraction of a sucrose gradient from LRV1-4-infected cells and used in Western immunoblot analysis to identify viral proteins from various isolates. Consistent with this result, in vitro-translated protein from cloned RNA was immunoprecipitated with the same antiserum. The putative capsid at times appeared as a doublet; relative amounts of the two species varied, depending on the method of purification.

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Year:  1993        PMID: 8350417      PMCID: PMC237969     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  9 in total

1.  Genomic structure and RNA polymerase activity in Leishmania virus.

Authors:  G Widmer; J L Patterson
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

2.  RNA polymerase activity is associated with viral particles isolated from Leishmania braziliensis subsp. guyanensis.

Authors:  G Widmer; M C Keenan; J L Patterson
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

3.  Transcriptional mapping of the amplified region encoding the dihydrofolate reductase-thymidylate synthase of Leishmania major reveals a high density of transcripts, including overlapping and antisense RNAs.

Authors:  G M Kapler; S M Beverley
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

4.  LR1: a candidate RNA virus of Leishmania.

Authors:  P I Tarr; R F Aline; B L Smiley; J Scholler; J Keithly; K Stuart
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

5.  Transcribing and replicating particles in a double-stranded RNA virus from Leishmania.

Authors:  R S Weeks; J L Patterson; K Stuart; G Widmer
Journal:  Mol Biochem Parasitol       Date:  1992-06       Impact factor: 1.759

6.  Molecular organization of Leishmania RNA virus 1.

Authors:  K D Stuart; R Weeks; L Guilbride; P J Myler
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-15       Impact factor: 11.205

7.  Successful transient introduction of Leishmania RNA virus into a virally infected and an uninfected strain of Leishmania.

Authors:  T C Armstrong; M C Keenan; G Widmer; J L Patterson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

8.  Characterization of a RNA virus from the parasite Leishmania.

Authors:  G Widmer; A M Comeau; D B Furlong; D F Wirth; J L Patterson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

9.  The double-stranded RNA genome of yeast virus L-A encodes its own putative RNA polymerase by fusing two open reading frames.

Authors:  T Icho; R B Wickner
Journal:  J Biol Chem       Date:  1989-04-25       Impact factor: 5.157

  9 in total
  15 in total

1.  Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.

Authors:  F Matthew Kuhlmann; John I Robinson; Gregory R Bluemling; Catherine Ronet; Nicolas Fasel; Stephen M Beverley
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-17       Impact factor: 11.205

2.  Hygromycin B resistance mediates elimination of Leishmania virus from persistently infected parasites.

Authors:  Y T Ro; S M Scheffter; J L Patterson
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

3.  Specific in vitro cleavage of a Leishmania virus capsid-RNA-dependent RNA polymerase polyprotein by a host cysteine-like protease.

Authors:  Y T Ro; S M Scheffter; J L Patterson
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

4.  Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.

Authors:  Erin A Brettmann; Jahangheer S Shaik; Haroun Zangger; Lon-Fye Lye; F Matthew Kuhlmann; Natalia S Akopyants; Dayna M Oschwald; Katherine L Owens; Suzanne M Hickerson; Catherine Ronet; Nicolas Fasel; Stephen M Beverley
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-18       Impact factor: 11.205

5.  Single-site cleavage in the 5'-untranslated region of Leishmaniavirus RNA is mediated by the viral capsid protein.

Authors:  K J MacBeth; J L Patterson
Journal:  Proc Natl Acad Sci U S A       Date:  1995-09-12       Impact factor: 11.205

6.  Mutational analysis of the capsid protein of Leishmania RNA virus LRV1-4.

Authors:  T L Cadd; K MacBeth; D Furlong; J L Patterson
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

7.  Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis.

Authors:  Annette Ives; Catherine Ronet; Florence Prevel; Giulia Ruzzante; Silvia Fuertes-Marraco; Frederic Schutz; Haroun Zangger; Melanie Revaz-Breton; Lon-Fye Lye; Suzanne M Hickerson; Stephen M Beverley; Hans Acha-Orbea; Pascal Launois; Nicolas Fasel; Slavica Masina
Journal:  Science       Date:  2011-02-11       Impact factor: 47.728

8.  Phylogenetic analysis of Leishmania RNA virus and Leishmania suggests ancient virus-parasite association.

Authors:  G Widmer; S Dooley
Journal:  Nucleic Acids Res       Date:  1995-06-25       Impact factor: 16.971

9.  Prevalence and Distribution of Leishmania RNA Virus 1 in Leishmania Parasites from French Guiana.

Authors:  Marine Ginouvès; Stéphane Simon; Eliane Bourreau; Vincent Lacoste; Catherine Ronet; Pierre Couppié; Mathieu Nacher; Magalie Demar; Ghislaine Prévot
Journal:  Am J Trop Med Hyg       Date:  2015-11-23       Impact factor: 2.345

10.  Synthesis of viruslike particles by expression of the putative capsid protein of Leishmania RNA virus in a recombinant baculovirus expression system.

Authors:  T L Cadd; J L Patterson
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103

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