| Literature DB >> 835006 |
M B Sporn, R A Squire, C C Brown, J M Smith, M L Wenk, S Springer.
Abstract
Transitional cell and squamous cell cancer of the bladder was induced in Wistar/Lewis female rats by direct instillation of N-methyl-N-nitrosourea into the bladder. Feeding of the synthetic retinoid, 13-cis-retinoid acid, inhibited the incidence and extent of bladder cancer in these rats, even when 13-cis-retinoic acid administration was begun after completion of the carcinogen treatment.Entities:
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Year: 1977 PMID： 835006 DOI： 10.1126/science.835006
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728