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Literature DB >> 6258577

Cellular uptake of retinoic acid in vitro.

Abstract

Incubation of chick embryo skin and mouse colon tumour 26 with [3H]retinoic acid resulted in the formation of a complex of retinoic acid and its cellular binding protein both in cytosol and in nuclei. Formation of the ligand--protein complex was temperature-dependent and increased with increases in retinoic acid concentration in the incubation medium. About 3--8% of the ligand present in the cytosol was associated with the nuclei.

Entities: Chemical Disease Species

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Year: 1980 PMID： 6258577 PMCID： PMC1162166 DOI： 10.1042/bj1900839

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

12 in total

1. Differential binding to soluble nuclear receptors and effects on cell viability of retinol and retinoic acid in cultured retinoblastoma cells.

Authors: B Wiggert; P Russell; M Lewis; G Chader
Journal: Biochem Biophys Res Commun Date: 1977-11-07 Impact factor: 3.575

1. Persistence of added retinoids in organ culture media during induction of mucous metaplasia and glandular morphogenesis in hamster cheek pouches.

Authors: M E Robinson; A M Gibbins; M H Hardy
Journal: Experientia Date: 1990-05-15

1 in total

Cellular uptake of retinoic acid in vitro.

1. Differential binding to soluble nuclear receptors and effects on cell viability of retinol and retinoic acid in cultured retinoblastoma cells.

2. Purification and properties of retinoic acid-binding protein from chick-embryo skin.

3. [Conservative treatment of recurrent papillomatosis of the urinary bladder with vitamin A acid. Preliminary report].

4. Localization of retinoic acid-binding protein in nuclei.

5. Possible role of retinoic acid binding protein in retinoid stimulation of embryonal carcinoma cell differentiation.

6. Determination of binding affinities of retinoids to retinoic acid-binding protein and serum albumin.

7. A retinoic acid-binding protein from chick embryo skin.

8. 13-cis-retinoic acid: inhibition of bladder carcinogenesis in the rat.

9. Retinoic acid-binding protein in normal tissues and experimental tumors.

10. Retinoic acid-binding protein in experimental tumors and in tissues with metastatic tumor foci.

1. Persistence of added retinoids in organ culture media during induction of mucous metaplasia and glandular morphogenesis in hamster cheek pouches.