M C Heng1. 1. Department of Medicine, UCLA San Fernando Valley Internal Medicine Program, Veterans Administration Medical Center, Sepulveda.
Abstract
BACKGROUND: Hyperbaric oxygen remains the sole treatment capable of inducing growth of new blood vessels. However, systemic hyperbaric oxygen therapy risks central nervous system and pulmonary toxicity. OBJECTIVE: To describe topical hyperbaric oxygen therapy for the treatment of recalcitrant open wounds. METHODS: Topical and systemic hyperbaric oxygen treatments are described and contrasted from one another. Applications of topical hyperbaric oxygen therapy are described. CONCLUSION: Topical hyperbaric oxygen therapy is useful only for open wounds. The advantages of topical hyperbaric oxygen therapy include low cost, the lack of systemic oxygen toxicity, and effectiveness, allowing this treatment to be prescribed for many patients early in the course of their disease rather than as a last resort.
BACKGROUND: Hyperbaric oxygen remains the sole treatment capable of inducing growth of new blood vessels. However, systemic hyperbaric oxygen therapy risks central nervous system and pulmonary toxicity. OBJECTIVE: To describe topical hyperbaric oxygen therapy for the treatment of recalcitrant open wounds. METHODS: Topical and systemic hyperbaric oxygen treatments are described and contrasted from one another. Applications of topical hyperbaric oxygen therapy are described. CONCLUSION: Topical hyperbaric oxygen therapy is useful only for open wounds. The advantages of topical hyperbaric oxygen therapy include low cost, the lack of systemic oxygentoxicity, and effectiveness, allowing this treatment to be prescribed for many patients early in the course of their disease rather than as a last resort.
Authors: Lohrasb R Sayadi; Derek A Banyard; Mary E Ziegler; Zaidal Obagi; Jordyne Prussak; Michael J Klopfer; Gregory Rd Evans; Alan D Widgerow Journal: Int Wound J Date: 2018-01-05 Impact factor: 3.315
Authors: Maximilian Petri; Ingo Stoffels; Klaus Griewank; Jithin Jose; Peter Engels; Andrea Schulz; Harald Pötzschke; Philipp Jansen; Dirk Schadendorf; Joachim Dissemond; Joachim Klode Journal: Mol Imaging Biol Date: 2018-02 Impact factor: 3.488