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Literature DB >> 26199891

Topical Oxygen for Chronic Wounds: A PRO/CON Debate.

Mesut Mutluoglu¹, Aslican Cakkalkurt², Gunalp Uzun³, Samil Aktas⁴.

Abstract

The role of oxygen in wound healing is universally accepted and does not require any further evidence; however the controversy as to whether oxygen delivery systems have the potential to improve wound healing remains to be concluded. Topical oxygen treatment (TOT) involves the delivery of 100% oxygen for a mean of 90 min, once a day at an atmospheric pressure slightly above 1 atm abs. The use of TOT gained increasing interest recently. The current manuscript will summarize the pros and cons of TOT in the view of the available literature.

Entities: Chemical

Keywords: Hyperbaric oxygen; Oxidative stress; Reactive oxygen species; Topical oxygen; Wound healing

Year: 2014 PMID： 26199891 PMCID： PMC4495745 DOI： 10.1016/j.jccw.2014.12.003

Source DB: PubMed Journal: J Am Coll Clin Wound Spec ISSN： 2213-5103

34 in total

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Authors: M Cho; T K Hunt; M Z Hussain
Journal: Am J Physiol Heart Circ Physiol Date: 2001-05 Impact factor: 4.733

8. Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair.

Authors: B Khodr; Z Khalil
Journal: Free Radic Biol Med Date: 2001-01-01 Impact factor: 7.376

9. Requirement of hydrogen peroxide generation in TGF-beta 1 signal transduction in human lung fibroblast cells: involvement of hydrogen peroxide and Ca2+ in TGF-beta 1-induced IL-6 expression.

Authors: E Junn; K N Lee; H R Ju; S H Han; J Y Im; H S Kang; T H Lee; Y S Bae; K S Ha; Z W Lee; S G Rhee; I Choi
Journal: J Immunol Date: 2000-08-15 Impact factor: 5.422

Topical Oxygen for Chronic Wounds: A PRO/CON Debate.

Review 1. Physiology of hyperbaric hyperoxia.

2. UHMS position statement: topical oxygen for chronic wounds.

3. Treatment of ulcers on the legs with hyperbaric oxygen.

4. The biosynthesis of collagen and its disorders (second of two parts).

5. Role of oxygen in repair processes.

6. The effect of hyperbaric oxygen on lower extremity ulcerations.

7. Hydrogen peroxide stimulates macrophage vascular endothelial growth factor release.

8. Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair.

9. Requirement of hydrogen peroxide generation in TGF-beta 1 signal transduction in human lung fibroblast cells: involvement of hydrogen peroxide and Ca2+ in TGF-beta 1-induced IL-6 expression.

10. Angiogenesis in necrotic ulcers treated with hyperbaric oxygen.

Review 1. Topical oxygen therapy & micro/nanobubbles: a new modality for tissue oxygen delivery.

Review 2. Oxygen Regulation in Development: Lessons from Embryogenesis towards Tissue Engineering.

3. Application of Topical Oxygen Therapy in Healing Dynamics of Diabetic Foot Ulcers - A Systematic Review.

Review 4. Integration of microbubbles with biomaterials in tissue engineering for pharmaceutical purposes.