Literature DB >> 8347398

Biological cloning of functionally diverse quasispecies of HIV-1.

R I Connor1, D W Notermans, H Mohri, Y Cao, D D Ho.   

Abstract

Twenty putative clones of HIV-1, derived by biological cloning from two different individuals, were characterized in vitro for functional activity and genotypic diversity. Many of the biological clones isolated by this method were genetically distinct, and could be further distinguished by differences in replication kinetics, host cell range, and/or cytopathicity. Our findings indicate that biological cloning by limiting dilution cultures is an effective method for isolating replication-competent, functionally diverse quasispecies of HIV-1.

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Year:  1993        PMID： 8347398     DOI： 10.1089/aid.1993.9.541

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  11 in total

1.  Immunization with a live, attenuated simian immunodeficiency virus vaccine leads to restriction of viral diversity in Rhesus macaques not protected from pathogenic challenge.

Authors:  D L Sodora; K E Sheridan; P A Marx; R I Connor
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

2.  The presence of host-derived HLA-DR1 on human immunodeficiency virus type 1 increases viral infectivity.

Authors:  R Cantin; J F Fortin; G Lamontagne; M Tremblay
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

3.  Cell-mediated infection of cervix derived epithelial cells with primary isolates of human immunodeficiency virus.

Authors:  X Tan; D M Phillips
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

4.  Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities.

Authors:  S Rusconi; M Moonis; D P Merrill; P V Pallai; E A Neidhardt; S K Singh; K J Willis; M S Osburne; A T Profy; J C Jenson; M S Hirsch
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

5.  Characterization of mutants of human immunodeficiency virus type 1 that have escaped neutralization by a monoclonal antibody to the gp120 V2 loop.

Authors:  H Yoshiyama; H Mo; J P Moore; D D Ho
Journal:  J Virol       Date:  1994-02       Impact factor: 5.103

6.  Effect of different donor cells on human immunodeficiency virus type 1 replication and selection in vitro.

Authors:  A I Spira; D D Ho
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103

7.  Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression.

Authors:  R I Connor; D D Ho
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103

8.  In vitro characterization of multidrug-resistant HIV-1 isolates from a recently infected patient associated with dual tropism and rapid disease progression.

Authors:  Hiroshi Mohri; Martin Markowitz
Journal:  J Acquir Immune Defic Syndr       Date:  2008-08-15       Impact factor: 3.731

9.  Molecular and biological analyses of quasispecies during evolution of a virulent simian immunodeficiency virus, SIVsmmPBj14.

Authors:  B Tao; P N Fultz
Journal:  J Virol       Date:  1995-04       Impact factor: 5.103

10.  Exposure to apoptotic activated CD4+ T cells induces maturation and APOBEC3G-mediated inhibition of HIV-1 infection in dendritic cells.

Authors:  Venkatramanan Mohanram; Ulrika Johansson; Annette E Sköld; Joshua Fink; Sushil Kumar Pathak; Barbro Mäkitalo; Lilian Walther-Jallow; Anna-Lena Spetz
Journal:  PLoS One       Date:  2011-06-16       Impact factor: 3.240
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