Literature DB >> 8343326

Increased expression of interleukin 6 mRNA in cardiac myxomas.

Y Seino1, U Ikeda, K Shimada.   

Abstract

In three patients with cardiac myxoma increased expression of interleukin 6 (IL-6) mRNA was found in the myxoma tissue by polymerase chain reaction (PCR) and in situ hybridisation. These cases suggest that IL-6 is overproduced in the myxoma tissue and secreted into the systemic circulatory system. This might contribute to the systemic inflammatory or autoimmune manifestations seen in cardiac myxoma. This study also showed the usefulness of PCR and in situ hybridisation for the evaluation of mRNA expression in small samples of tissue.

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Year:  1993        PMID： 8343326      PMCID： PMC1025174          DOI： 10.1136/hrt.69.6.565

Source DB:  PubMed          Journal:  Br Heart J        ISSN： 0007-0769


  9 in total

1.  Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction.

Authors:  A M Feldman; P E Ray; C M Silan; J A Mercer; W Minobe; M R Bristow
Journal:  Circulation       Date:  1991-06       Impact factor: 29.690

2.  Increased serum interleukin-6 in cardiac myxoma.

Authors:  T Saji; E Yanagawa; H Matsuura; S Yamamoto; T Ishikita; N Matsuo; K Yoshirwara; Y Takanashi
Journal:  Am Heart J       Date:  1991-08       Impact factor: 4.749

3.  Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

Authors:  J N Wilcox; K M Smith; L T Williams; S M Schwartz; D Gordon
Journal:  J Clin Invest       Date:  1988-09       Impact factor: 14.808

4.  Interleukin 6 gene transcripts are expressed in atherosclerotic lesions of genetically hyperlipidemic rabbits.

Authors:  U Ikeda; M Ikeda; Y Seino; M Takahashi; S Kano; K Shimada
Journal:  Atherosclerosis       Date:  1992-02       Impact factor: 5.162

5.  Constitutive production of interleukin-6 and immunologic features in cardiac myxomas.

Authors:  M Jourdan; R Bataille; J Seguin; X G Zhang; P A Chaptal; B Klein
Journal:  Arthritis Rheum       Date:  1990-03

6.  Interleukin 6 stimulates growth of vascular smooth muscle cells in a PDGF-dependent manner.

Authors:  U Ikeda; M Ikeda; T Oohara; A Oguchi; T Kamitani; Y Tsuruya; S Kano
Journal:  Am J Physiol       Date:  1991-05

7.  Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

Authors:  T Hirano; T Taga; K Yasukawa; K Nakajima; N Nakano; F Takatsuki; M Shimizu; A Murashima; S Tsunasawa; F Sakiyama
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

8.  Serum interleukin 6 levels become elevated in acute myocardial infarction.

Authors:  U Ikeda; F Ohkawa; Y Seino; K Yamamoto; Y Hidaka; T Kasahara; T Kawai; K Shimada
Journal:  J Mol Cell Cardiol       Date:  1992-06       Impact factor: 5.000

9.  Quantitation of mRNA by the polymerase chain reaction.

Authors:  A M Wang; M V Doyle; D F Mark
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205
  9 in total
  8 in total

1.  Systemic embolisation as presentation and recurrence of cardiac myxoma two years after surgery.

Authors:  C Liesting; F Z Ramjankhan; L A van Herwerden; M J M Kofflard
Journal:  Neth Heart J       Date:  2010-10       Impact factor: 2.380

2.  Imitation of a chronic recurrent inflammatory illness by a cardiac myxoma.

Authors:  J P Pfammatter; T Iff; P Schüpbach
Journal:  Eur J Pediatr       Date:  1996-08       Impact factor: 3.183

3.  The role of interleukin-6 in cases of cardiac myxoma. Clinical features, immunologic abnormalities, and a possible role in recurrence.

Authors:  C E Mendoza; M F Rosado; L Bernal
Journal:  Tex Heart Inst J       Date:  2001

4.  [Atrial myxoma with clinical signs of systemic inflammatory disease].

Authors:  I Hartig; E-G Kraatz; H-W Beurich; F Moosig
Journal:  Z Rheumatol       Date:  2014-04       Impact factor: 1.372

Review 5.  Pseudovasculitis: mechanisms of vascular injury and clinical spectrum.

Authors:  Rafael Grau
Journal:  Curr Rheumatol Rep       Date:  2002-02       Impact factor: 4.686

6.  An unusual presentation of atrial myxoma with haematuria and proteinuria.

Authors:  James R Bushnell; Charles Weston; Lazarus Karamadoukis
Journal:  NDT Plus       Date:  2011-01-21

7.  Predictors of Normalization of Circulating Interleukin-6 after Cardiac Myxoma Resection.

Authors:  Shi-Min Yuan; Hui-Zhen Lin
Journal:  Braz J Cardiovasc Surg       Date:  2019 Jan-Feb

8.  An unusual case of sudden collapse in the immediate postoperative period in a young healthy female with myxofibroma of the maxilla.

Authors:  Manila Singh; Saket Singh
Journal:  Case Rep Anesthesiol       Date:  2013-07-30
  8 in total

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