Literature DB >> 8340604

Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.

C Féray1, M Gigou, D Samuel, J Bernuau, H Bismuth, C Bréchot.   

Abstract

The presence of mutants of the precore region of the hepatitis B virus genome was investigated in French patients with fulminant hepatitis. Only one of the 10 subjects had a detectable mutation by direct sequencing. On the other hand, 2/10 and 3/10 had evidence of coinfection by hepatitis D virus and hepatitis C virus. These results indicate that the precore stop mutation at codon 28 is not a general condition in fulminant hepatitis B and might reflect epidemiological factors.

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Year:  1993        PMID： 8340604     DOI： 10.1016/s0168-8278(05)80019-4

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


  7 in total

1.  Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic.

Authors:  C M Chu; C T Yeh; C T Chiu; I S Sheen; Y F Liaw
Journal:  J Clin Microbiol       Date:  1996-07       Impact factor: 5.948

2.  Molecular epidemiology of an outbreak of fulminant hepatitis B.

Authors:  N Petrosillo; G Ippolito; L Solforosi; P E Varaldo; M Clementi; A Manzin
Journal:  J Clin Microbiol       Date:  2000-08       Impact factor: 5.948

Review 3.  Etiology and management of fulminant hepatic failure.

Authors:  Javier Vaquero; Andres T Blei
Journal:  Curr Gastroenterol Rep       Date:  2003-02

4.  Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba, Japan.

Authors:  T Imamura; O Yokosuka; T Kurihara; T Kanda; K Fukai; F Imazeki; H Saisho
Journal:  Gut       Date:  2003-11       Impact factor: 23.059

5.  Association of hepatitis B virus subgenotypes and basal core promoter/precore region variants with the clinical features of patients with acute hepatitis.

Authors:  Kazuhiko Hayashi; Yoshiaki Katano; Yasushi Takeda; Takashi Honda; Masatoshi Ishigami; Akihiro Itoh; Yoshiki Hirooka; Isao Nakano; Kentaro Yoshioka; Hidenori Toyoda; Takashi Kumada; Hidemi Goto
Journal:  J Gastroenterol       Date:  2008-07-23       Impact factor: 7.527

6.  Complete hepatitis B virus genome analysis in HBsAg positive mothers and their infants with fulminant hepatitis B.

Authors:  Michael Friedt; Patrick Gerner; Philip Wintermeyer; Stefan Wirth
Journal:  BMC Gastroenterol       Date:  2004-06-08       Impact factor: 3.067

7.  Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.

Authors:  K C Koh; H S Lee; C Y Kim
Journal:  Korean J Intern Med       Date:  1994-07       Impact factor: 2.884
  7 in total

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