Literature DB >> 8784599

Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic.

C M Chu1, C T Yeh, C T Chiu, I S Sheen, Y F Liaw.   

Abstract

By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. The precore TAG mutant prevails in acute and chronic hepatitis B of various severity in this area where hepatitis B is endemic.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8784599      PMCID： PMC229124     

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  23 in total

1.  Fulminant hepatitis B: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e antigen.

Authors:  Y Kosaka; K Takase; M Kojima; M Shimizu; K Inoue; M Yoshiba; S Tanaka; Y Akahane; H Okamoto; F Tsuda
Journal:  Gastroenterology       Date:  1991-04       Impact factor: 22.682

2.  A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis.

Authors:  T J Liang; K Hasegawa; N Rimon; J R Wands; E Ben-Porath
Journal:  N Engl J Med       Date:  1991-06-13       Impact factor: 91.245

3.  Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis.

Authors:  M Omata; T Ehata; O Yokosuka; K Hosoda; M Ohto
Journal:  N Engl J Med       Date:  1991-06-13       Impact factor: 91.245

4.  Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis.

Authors:  M R Brunetto; M M Giarin; F Oliveri; E Chiaberge; M Baldi; A Alfarano; A Serra; G Saracco; G Verme; H Will
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

5.  Hepatitis B antigen (HBSAg) and/or antibodies (anti-HBS and anti-HBC) in fulminant hepatitis: pathogenic and prognostic significance.

Authors:  C G Trepo; D Robert; J Motin; D Trepo; M Sepetjian; A M Prince
Journal:  Gut       Date:  1976-01       Impact factor: 23.059

6.  Precore mutant of hepatitis B virus in childhood fulminant hepatitis B: an infrequent association.

Authors:  H Y Hsu; M H Chang; C Y Lee; K H Hsieh; Y H Ni; P J Chen; D S Chen
Journal:  J Infect Dis       Date:  1995-04       Impact factor: 5.226

7.  Enhanced HBsAb production in pathogenesis of fulminant viral hepatitis type B.

Authors:  I L Woolf; N El Sheikh; H Cullens; W M Lee; A L Eddleston; R Williams; A J Zuckerman
Journal:  Br Med J       Date:  1976-09-18

8.  Application of natural and amplification created restriction sites for the diagnosis of PKU mutations.

Authors:  H G Eiken; E Odland; H Boman; L Skjelkvåle; L F Engebretsen; J Apold
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

9.  Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis.

Authors:  W F Carman; E A Fagan; S Hadziyannis; P Karayiannis; N C Tassopoulos; R Williams; H C Thomas
Journal:  Hepatology       Date:  1991-08       Impact factor: 17.425

10.  Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen.

Authors:  H Okamoto; S Yotsumoto; Y Akahane; T Yamanaka; Y Miyazaki; Y Sugai; F Tsuda; T Tanaka; Y Miyakawa; M Mayumi
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103
View more
  7 in total

1.  Viral load, genotypes, and mutants in hepatitis B virus-related hepatocellular carcinoma: special emphasis on patients with early hepatocellular carcinoma.

Authors:  Chia-Ming Chu; Chen-Chun Lin; Shi-Ming Lin; Deng-Yn Lin; Yun-Fan Liaw
Journal:  Dig Dis Sci       Date:  2011-08-12       Impact factor: 3.199

2.  Role of viral factors in the natural course and therapy of chronic hepatitis B.

Authors:  Jia-Horng Kao
Journal:  Hepatol Int       Date:  2007-10-12       Impact factor: 6.047

3.  Precore stop mutant in HBeAg-positive patients with chronic hepatitis B: clinical characteristics and correlation with the course of HBeAg-to-anti-HBe seroconversion.

Authors:  Chia-Ming Chu; Chau-Ting Yeh; Ching-Song Lee; I-Shyan Sheen; Yun-Fan Liaw
Journal:  J Clin Microbiol       Date:  2002-01       Impact factor: 5.948

4.  Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba, Japan.

Authors:  T Imamura; O Yokosuka; T Kurihara; T Kanda; K Fukai; F Imazeki; H Saisho
Journal:  Gut       Date:  2003-11       Impact factor: 23.059

Review 5.  New perspective on the natural course of chronic HBV infection.

Authors:  Yong-Yuan Zhang; Ke-Qin Hu; Zhongping Duan
Journal:  Front Med       Date:  2014-05-29       Impact factor: 4.592

6.  Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection.

Authors:  C-M Chu; C-C Lin; Y-C Chen; W-J Jeng; S-M Lin; Y-F Liaw
Journal:  Br J Cancer       Date:  2012-10-18       Impact factor: 7.640

7.  G1896A Precore Mutation and Association With HBeAg Status, Genotype and Clinical Status in Patients With Chronic Hepatitis B.

Authors:  Jeyanthi Suppiah; Rozainanee Mohd Zain; Norazlah Bahari; Salbiah Haji Nawi; Zainah Saat
Journal:  Hepat Mon       Date:  2015-10-28       Impact factor: 0.660
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.