Literature DB >> 8340113

Regional chromosomal assignment of the Kell blood group locus (KEL) to chromosome 7q33-q35 by fluorescence in situ hybridization: evidence for the polypeptide nature of antigenic variation.

M T Murphy1, N Morrison, J S Miles, R H Fraser, N K Spurr, E Boyd.   

Abstract

The gene encoding the Kell blood group polypeptide has been localized to chromosome 7q33-35 by in situ hybridization using a biotinylated 1.1-kb DNA fragment containing the 3' half of the human cDNA. This assignment is in accord with genetic localization using antigenic variation as a marker, and strongly suggests that Kell antigenic determinants are part of the polypeptide chain rather than the associated sugar molecules.

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Year:  1993        PMID： 8340113     DOI： 10.1007/bf00205085

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  23 in total

1.  Reverse chromosome painting: a method for the rapid analysis of aberrant chromosomes in clinical cytogenetics.

Authors:  N P Carter; M A Ferguson-Smith; M T Perryman; H Telenius; A H Pelmear; M A Leversha; M T Glancy; S L Wood; K Cook; H M Dyson
Journal:  J Med Genet       Date:  1992-05       Impact factor: 6.318

2.  Genetic linkage between the Kell blood group system and prolactin-inducible protein loci: provisional assignment of KEL to chromosome 7.

Authors:  T Zelinski; G Coghlan; Y Myal; R P Shiu; S Philipps; L White; M Lewis
Journal:  Ann Hum Genet       Date:  1991-05       Impact factor: 1.670

3.  Kell blood group antigens are part of a 93,000-dalton red cell membrane protein.

Authors:  C M Redman; G Avellino; S R Pfeffer; T K Mukherjee; M Nichols; P Rubinstein; W L Marsh
Journal:  J Biol Chem       Date:  1986-07-15       Impact factor: 5.157

4.  A cytochrome P-450 gene family mapped to human chromosome 19.

Authors:  I R Phillips; E A Shephard; S Povey; M B Davis; G Kelsey; M Monteiro; L F West; J Cowell
Journal:  Ann Hum Genet       Date:  1985-10       Impact factor: 1.670

5.  Regulation of expression of liver-specific enzymes. III. Further analysis of a series of rat hepatoma X human somatic cell hybrids.

Authors:  C M Kielty; S Povey; D A Hopkinson
Journal:  Ann Hum Genet       Date:  1982-10       Impact factor: 1.670

6.  Chromosomal localization of human cellular homologues of two viral oncogenes.

Authors:  N Heisterkamp; J Groffen; J R Stephenson; N K Spurr; P N Goodfellow; E Solomon; B Carritt; W F Bodmer
Journal:  Nature       Date:  1982-10-21       Impact factor: 49.962

7.  Assignment of the human locus determining phosphoglycolate phosphatase (PGP) to chromosome 16.

Authors:  S Povey; S J Jeremiah; R F Barker; D A Hopkinson; E B Robson; P J Cook; E Solomon; M Bobrow; B Carritt; K E Buckton
Journal:  Ann Hum Genet       Date:  1980-01       Impact factor: 1.670

8.  Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

Authors:  D Pinkel; T Straume; J W Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

9.  Immunoglobulin heavy chain genes in humans are located on chromosome.

Authors:  M J Hobart; T H Rabbitts; P N Goodfellow; E Solomon; S Chambers; N Spurr; S Povey
Journal:  Ann Hum Genet       Date:  1981-10       Impact factor: 1.670

10.  Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): multiple miniexons and separate 5' untranslated regions.

Authors:  L D'Adamio; M A Shipp; E L Masteller; E L Reinherz
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205
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