Literature DB >> 8339339

Analgesic component of Notopterygium incisum Ting.

E Okuyama1, S Nishimura, S Ohmori, Y Ozaki, M Satake, M Yamazaki.   

Abstract

Notopterol was identified as the analgesic component of Notopterygium incisum TING by using the acetic acid-induced writhing method. Notopterol also indicated an anti-inflammatory activity by its inhibitory effect in the vascular permeability test. The intensive prolongation of pentobarbital-induced hypnosis was possibly caused by its inhibitory effect on the drug metabolism in liver. Pharmacological differences between the analgesic components of N. incisum, Aralia cordata and Angelica pubescens were also discussed.

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Year:  1993        PMID： 8339339     DOI： 10.1248/cpb.41.926

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  7 in total

1.  New guaiane sesquiterpenes and furanocoumarins from Notopterygium incisum.

Authors:  Shi-Biao Wu; Yun Zhao; Hui Fan; Ying-He Hu; Mark T Hamann; Jiang-Nan Peng; Courtney M Starks; Mark O'Neil-Johnson; Jin-Feng Hu
Journal:  Planta Med       Date:  2008-11-07       Impact factor: 3.352

2.  Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors.

Authors:  Zhongze Ma; Wei Xu; Lee-Yuan Liu-Chen; David Y W Lee
Journal:  Bioorg Med Chem       Date:  2007-12-31       Impact factor: 3.641

3.  Polyyne hybrid compounds from Notopterygium incisum with peroxisome proliferator-activated receptor gamma agonistic effects.

Authors:  Xin Liu; Olaf Kunert; Martina Blunder; Nanang Fakhrudin; Stefan M Noha; Clemens Malainer; Andreas Schinkovitz; Elke H Heiss; Atanas G Atanasov; Manfred Kollroser; Daniela Schuster; Verena M Dirsch; Rudolf Bauer
Journal:  J Nat Prod       Date:  2014-10-21       Impact factor: 4.050

4.  The pharmacokinetics, bioavailability and excretion of bergapten after oral and intravenous administration in rats using high performance liquid chromatography with fluorescence detection.

Authors:  Xie-An Yu; John Teye Azietaku; Jin Li; Mingrui An; Jun He; Jia Hao; Jun Cao; Yan-Xu Chang
Journal:  Chem Cent J       Date:  2016-10-14       Impact factor: 4.215

5.  Simultaneous Determination of Bergapten, Imperatorin, Notopterol, and Isoimperatorin in Rat Plasma by High Performance Liquid Chromatography with Fluorescence Detection and Its Application to Pharmacokinetic and Excretion Study after Oral Administration of Notopterygium incisum Extract.

Authors:  John Teye Azietaku; Xie-An Yu; Jin Li; Jia Hao; Jun Cao; Mingrui An; Zhijing Tan; Yan-Xu Chang
Journal:  Int J Anal Chem       Date:  2016-12-26       Impact factor: 1.885

6.  Anti-Inflammatory Phenolic Acid Esters from the Roots and Rhizomes of Notopterygium incisium and Their Permeability in the Human Caco-2 Monolayer Cell Model.

Authors:  Xiu-Wen Wu; Wei Wei; Xiu-Wei Yang; You-Bo Zhang; Wei Xu; Yan-Fang Yang; Guo-Yue Zhong; Hong-Ning Liu; Shi-Lin Yang
Journal:  Molecules       Date:  2017-06-04       Impact factor: 4.411

7.  Chinese Herbal Medicines for Rheumatoid Arthritis: Text-Mining the Classical Literature for Potentially Effective Natural Products.

Authors:  Xuan Xia; Brian H May; Anthony Lin Zhang; Xinfeng Guo; Chuanjian Lu; Charlie C Xue; Qingchun Huang
Journal:  Evid Based Complement Alternat Med       Date:  2020-04-28       Impact factor: 2.629
  7 in total

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