Literature DB >> 833830

Synthesis and antiinflammatory and hypnotic activity of 5-alkoxy-3-(N-substituted carbamoyl)-1-phenylpyrazoles.

S Sugiura, S Ohno, O Ohtani, K Izumi, T Kitamikado, H Asai, K Kato.   

Abstract

5-Alkoxy-3-(N-substituted carbamoly)-1-phenylpyrazoles were prepared and tested for antiinflammatory and hypnotic activity. Four compounds showed antiinflammatory activity and three possessed hypnotic properties.

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Year:  1977        PMID： 833830     DOI： 10.1021/jm00211a016

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  4 in total

1.  Antimicrobial screening and one-pot synthesis of 4-(substituted-anilinomethyl)-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives.

Authors:  Neelima Goel; Sushma Drabu; Obaid Afzal; Sandhya Bawa
Journal:  J Pharm Bioallied Sci       Date:  2014-10

2.  Synthesis of Some New 3, 5-Bis (substituted) Pyrazoles and Isoxazoles Based on (N'(1)E, N'(3)E)- N'(1), N'(3)-Bis (3, 4, 5-substitutedbenzlidene) Malonohydrazide under Solvothermal Conditions.

Authors:  Ebraheem Abdu Musad; Kuriya Madavu Lokanatha Rai; Kullaiah Byrappa
Journal:  Int J Biomed Sci       Date:  2010-03

3.  β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies.

Authors:  Ramasamy Venkat Ragavan; Kalavathi Murugan Kumar; Vijayaparthasarathi Vijayakumar; Sundaramoorthy Sarveswari; Sudha Ramaiah; Anand Anbarasu; Sivashanmugam Karthikeyan; Periyasamy Giridharan; Nalilu Suchetha Kumari
Journal:  Org Med Chem Lett       Date:  2013-07-19

4.  Inhibitory effect of N-ethyl-3-amino-5-oxo-4-phenyl-2,5-dihydro-1H-pyrazole-1-carbothioamide on Haemophilus spp. planktonic or biofilm-forming cells.

Authors:  Urszula Kosikowska; Anna Malm; Monika Pitucha; Barbara Rajtar; Malgorzata Polz-Dacewicz
Journal:  Med Chem Res       Date:  2013-08-23       Impact factor: 1.965
  4 in total

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