Literature DB >> 8337356

Radiation-induced chromosomal aberrations in the bone marrow of mice exposed to various doses of gamma radiation.

G C Jagetia1.   

Abstract

The occurrence of chromosomal aberrations was studied at 1-14 days post-exposure in female BALB/c mice exposed to various doses of gamma radiation. The frequency of abnormal cells, chromatid and chromosome breaks, dicentrics, centric rings, acentric fragments and total aberrations increased with exposure dose, and it was highest at 7 Gy. A peak was recorded on day 1 post-exposure with a gradual decline thereafter. The chromosomal aberration yield reached a nadir on day 14 post-irradiation, without restoration to the control level. The best fit for the present data was by a linear-quadratic relationship between dose of radiation and the frequency of chromosomal aberrations.

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Year:  1993        PMID： 8337356     DOI： 10.1007/bf01212797

Source DB:  PubMed          Journal:  Radiat Environ Biophys        ISSN： 0301-634X            Impact factor:   1.925


  19 in total

1.  Chromosome preparations of leukocytes cultured from human peripheral blood.

Authors:  P S MOORHEAD; P C NOWELL; W J MELLMAN; D M BATTIPS; D A HUNGERFORD
Journal:  Exp Cell Res       Date:  1960-09       Impact factor: 3.905

2.  Chromosome protection by WR-2721 and MPG-single and combination treatments.

Authors:  B Thomas; P U Devi
Journal:  Strahlenther Onkol       Date:  1987-12       Impact factor: 3.621

3.  Chromosome Aberrations Induced by X-Rays.

Authors:  K Sax
Journal:  Genetics       Date:  1938-09       Impact factor: 4.562

4.  Treatment of mice with a herbal preparation (Liv. 52) reduces the frequency of radiation-induced chromosome damage in bone marrow.

Authors:  G C Jagetia; N G Ganapathi
Journal:  Mutat Res       Date:  1991-10       Impact factor: 2.433

5.  Chromosome aberration frequencies produced by a 70-MeV proton beam.

Authors:  S Matsubara; H Ohara; T Hiraoka; S Koike; K Ando; H Yamaguchi; Y Kuwabara; M Hoshina; S Suzuki
Journal:  Radiat Res       Date:  1990-08       Impact factor: 2.841

6.  Production of chromosome aberrations, micronuclei, and sister-chromatid exchanges by 24-keV epithermal neutrons in human G0 lymphocytes.

Authors:  S Z Aghamohammadi; D T Goodhead; J R Savage
Journal:  Mutat Res       Date:  1989-04       Impact factor: 2.433

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Authors:  J G Brewen; R J Preston
Journal:  Nat New Biol       Date:  1973-07-25

8.  The effect of x-ray induced mitotic delay on chromosome aberration yields in human lymphocytes.

Authors:  D C Lloyd; G W Dolphin; R J Purrott; P A Tipper
Journal:  Mutat Res       Date:  1977-03       Impact factor: 2.433

9.  The induction of chromosome aberrations in human lymphocytes by in vitro irradiation with alpha-particles from plutonium-239.

Authors:  R J Purrott; A A Edwards; D C Lloyd; J W Stather
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1980-09

10.  A cytogenetic comparison of the responses of mouse and human peripheral blood lymphocytes to 60Co gamma radiation.

Authors:  A D Kligerman; E C Halperin; G L Erexson; G Honoré; B Westbrook-Collins; J W Allen
Journal:  Radiat Res       Date:  1988-08       Impact factor: 2.841
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  2 in total

1.  No Evidence for the In Vivo Induction of Genomic Instability by Low Doses of CS Gamma Rays in Bone Marrow Cells of BALB/CJ and C57BL/6J Mice.

Authors:  Kanokporn Noy Rithidech; Chatchanok Udomtanakunchai; Louise M Honikel; Elbert B Whorton
Journal:  Dose Response       Date:  2011-08-11       Impact factor: 2.658

Review 2.  Utilization of cytogenetic biomarkers as a tool for assessment of radiation injury and evaluation of radiomodulatory effects of various medicinal plants - a review.

Authors:  Ravindra M Samarth; Meenakshi Samarth; Yoshihisa Matsumoto
Journal:  Drug Des Devel Ther       Date:  2015-09-25       Impact factor: 4.162
  2 in total

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