Literature DB >> 8335390

Experimental model of congenital syphilis.

A Kajdacsy-Balla1, A Howeedy, O Bagasra.   

Abstract

Female LSH hamsters infected with Treponema pallidum subsp, endemicum before pregnancy or during early pregnancy transmit a form of syphilis to the fetus that is similar to human congenital syphilis. The offspring develops rhinitis, skin rash, failure to thrive, and hepatosplenomegaly. T. pallidum is detectable in their livers, spleens, and nasal secretions. Immunoglobulin M antibodies are detected in the serum.

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Year:  1993        PMID： 8335390      PMCID： PMC281041          DOI： 10.1128/iai.61.8.3559-3561.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  7 in total

1.  Syphilis in the Syrian hamster. A model of human venereal and congenital syphilis.

Authors:  A Kajdacsy-Balla; A Howeedy; O Bagasra
Journal:  Am J Pathol       Date:  1987-03       Impact factor: 4.307

2.  LSH hamster model of syphilitic infection and transfer of resistance with immune T cells.

Authors:  R F Schell; J L LeFrock; J K Chan; O Bagasra
Journal:  Adv Exp Med Biol       Date:  1981       Impact factor: 2.622

3.  Ability of macrophages to process and present Treponema pallidum Bosnia A strain antigens in experimental syphilis of syrian hamsters.

Authors:  O Bagasra; I Damjanov
Journal:  Infect Immun       Date:  1982-04       Impact factor: 3.441

4.  Treponemal infection specifically enhances node T-cell regulation of macrophage activity.

Authors:  D R Tabor; O Bagasra; R F Jacobs
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

5.  Lymphocyte function in experimental endemic syphilis of Syrian hamsters.

Authors:  O Bagasra; H Kushner; S Hashemi
Journal:  Immunology       Date:  1985-09       Impact factor: 7.397

6.  Endemic syphilis: transfer of resistance to Treponema pallidum strain Bosnia A in hamsters with a cell suspension enriched in thymus-derived cells.

Authors:  R F Schell; J K Chan; J L LeFrock; O Bagasra
Journal:  J Infect Dis       Date:  1980-06       Impact factor: 5.226

7.  Experimental congenital syphilis in rabbits.

Authors:  T J Fitzgerald
Journal:  Can J Microbiol       Date:  1985-09       Impact factor: 2.419
  7 in total
  2 in total

1.  Modeling the Mycobacterium tuberculosis Granuloma - the Critical Battlefield in Host Immunity and Disease.

Authors:  Evelyn Guirado; Larry S Schlesinger
Journal:  Front Immunol       Date:  2013-04-22       Impact factor: 7.561

Review 2.  Tuberculous Granuloma: Emerging Insights From Proteomics and Metabolomics.

Authors:  Abisola Regina Sholeye; Aurelia A Williams; Du Toit Loots; A Marceline Tutu van Furth; Martijn van der Kuip; Shayne Mason
Journal:  Front Neurol       Date:  2022-03-21       Impact factor: 4.003
  2 in total

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