OBJECTIVE: Our objective was to examine the association between preterm delivery and bacterial vaginosis in early and late pregnancy. STUDY DESIGN: We evaluated 490 pregnant women at three hospitals in Jakarta, Indonesia, for bacterial vaginosis at 16 to 20 weeks' and 28 to 32 weeks' gestation and observed them through delivery. RESULTS: We found significant associations between preterm delivery (gestational age < 37 weeks) and bacterial vaginosis diagnosed at 16 to 20 weeks' gestation (odds ratio 2.0, 95% confidence interval 1.0 to 3.9) but not with bacterial vaginosis diagnosed at 28 to 32 weeks' gestation (odds ratio 1.5, 95% confidence interval 0.7 to 3.0). The rates of preterm delivery were almost doubled for women who had bacterial vaginosis in early pregnancy (20.5%) as compared with women who had bacterial vaginosis only in late pregnancy (10.7%). CONCLUSION: Only bacterial vaginosis diagnosed early in the second trimester of pregnancy plays a major role as a risk factor for preterm delivery.
OBJECTIVE: Our objective was to examine the association between preterm delivery and bacterial vaginosis in early and late pregnancy. STUDY DESIGN: We evaluated 490 pregnant women at three hospitals in Jakarta, Indonesia, for bacterial vaginosis at 16 to 20 weeks' and 28 to 32 weeks' gestation and observed them through delivery. RESULTS: We found significant associations between preterm delivery (gestational age < 37 weeks) and bacterial vaginosis diagnosed at 16 to 20 weeks' gestation (odds ratio 2.0, 95% confidence interval 1.0 to 3.9) but not with bacterial vaginosis diagnosed at 28 to 32 weeks' gestation (odds ratio 1.5, 95% confidence interval 0.7 to 3.0). The rates of preterm delivery were almost doubled for women who had bacterial vaginosis in early pregnancy (20.5%) as compared with women who had bacterial vaginosis only in late pregnancy (10.7%). CONCLUSION: Only bacterial vaginosis diagnosed early in the second trimester of pregnancy plays a major role as a risk factor for preterm delivery.
Authors: Ronald F Lamont; Chia-Ling Nhan-Chang; Jack D Sobel; Kimberly Workowski; Agustin Conde-Agudelo; Roberto Romero Journal: Am J Obstet Gynecol Date: 2011-04-02 Impact factor: 8.661
Authors: Marina Catallozzi; Camille Y Williams; Gregory D Zimet; Katharine M Hargreaves; Shari E Gelber; Adam J Ratner; Lawrence R Stanberry; Susan L Rosenthal Journal: Sex Health Date: 2014-09 Impact factor: 2.706
Authors: Wanda M Wenman; Ivanna V Tataryn; Michel R Joffres; Rachelle Pearson; Michael Ga Grace; William L Albritton; Errol Prasad Journal: Can J Infect Dis Date: 2002-09
Authors: Enesia Banda Chaponda; R Matthew Chico; Jane Bruce; Charles Michelo; Bellington Vwalika; Sungano Mharakurwa; Mike Chaponda; James Chipeta; Daniel Chandramohan Journal: Am J Trop Med Hyg Date: 2016-09-26 Impact factor: 2.345