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Literature DB >> 8326528

Effects of thymosin on the secretion of the sexual hormone in rats with experimental varicocele.

J Zeng¹, Y S Zhang, Q Y Zhuang, S W Zhou.

Abstract

Hormonal abnormality in experimental varicocele induced by partial ligation of left renal vein and the effect of thymosin (fraction 5) on the secretion of the sexual hormone were studied in rats. Serum testosterone level was lowered after varicocele formation, but could be reversed or increased by intraperitoneal administration of thymosin 5 mg/rat twice a week for 4 weeks with concomitant increase of testicular testosterone content. Changes in FSH and LH both in serum and testis, determined with immunoassay method as that of testosterone, were insignificant as compared with control or thymosin treated groups.

Entities: Chemical Disease Species

Mesh：

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Year: 1993 PMID： 8326528 DOI： 10.1007/bf02886592

Source DB: PubMed Journal: J Tongji Med Univ ISSN： 0257-716X

11 in total

Review 1. The endocrinology of varicoceles.

Authors: R W Hudson
Journal: Fertil Steril Date: 1988-02 Impact factor: 7.329

2. Thymosin alpha 1 levels in human seminal plasma and follicular fluid: implication in germ cell function.

Authors: R K Naz; P H Naylor; A L Goldstein
Journal: Int J Fertil Date: 1987 Sep-Oct

3. Evidence that thymosins and other biologic response modifiers can function as neuroactive immunotransmitters.

Authors: N R Hall; J P McGillis; B L Spangelo; A L Goldstein
Journal: J Immunol Date: 1985-08 Impact factor: 5.422

4. [Effects of thymosin (fraction 5) on the endocrine function of the testis in mice].

Authors: V M Chesnokova; E V Ignat'eva; L N Ivanova
Journal: Biull Eksp Biol Med Date: 1988-10

5. Absence of gonadotropin-releasing hormone receptors in human gonadal tissue.

Authors: R N Clayton; I T Huhtaniemi
Journal: Nature Date: 1982-09-02 Impact factor: 49.962

6. Thymosin stimulates secretion of luteinizing hormone-releasing factor.

Authors: R W Rebar; A Miyake; T L Low; A L Goldstein
Journal: Science Date: 1981-11-06 Impact factor: 47.728

7. [Effect of thymosin (fraction 5) on the development of functional activity of the adrenals and gonads in genetically athymic mice].

Authors: E V Ignat'eva; V M Chesnokova; V M Iunker; L N Ivanova; O M Tepelina
Journal: Probl Endokrinol (Mosk) Date: 1988 Nov-Dec

Effects of thymosin on the secretion of the sexual hormone in rats with experimental varicocele.

Review 1. The endocrinology of varicoceles.

2. Thymosin alpha 1 levels in human seminal plasma and follicular fluid: implication in germ cell function.

3. Evidence that thymosins and other biologic response modifiers can function as neuroactive immunotransmitters.

4. [Effects of thymosin (fraction 5) on the endocrine function of the testis in mice].

5. Absence of gonadotropin-releasing hormone receptors in human gonadal tissue.

6. Thymosin stimulates secretion of luteinizing hormone-releasing factor.

7. [Effect of thymosin (fraction 5) on the development of functional activity of the adrenals and gonads in genetically athymic mice].

8. Endocrine evaluation in infertile men with varicocele.

9. Evidence for thymus involvement in development of adrenal and gonadal endocrine functions in mice.

10. A thymus factor influences the in vitro testosterone secretion of Leydig cells in the rat.

1. The influence of thymectomy on germ-cells of the testis in mice.