Literature DB >> 8323336

Role of hiatal hernia in delaying acid clearance.

R J Stewart1, B T Johnston, V E Boston, J Dodge.   

Abstract

The aim of this study was to assess prospectively the relationship of a hiatal hernia to gastro-oesophageal reflux. Ninety five children with symptoms of gastro-oesophageal reflux in whom reflux was demonstrated radiologically were investigated. Oesophageal pH monitoring for 18 hours and endoscopy were performed in all patients. On the basis of radiology, patients were divided into those with hiatal hernia (n = 37) and those without (n = 58). Both groups had the same number of reflux episodes on pH monitoring. However, the median duration of the longest episode was significantly greater in the hiatal hernia group (30 min v 19 min), as was the number of reflux episodes longer than five minutes (5 v 4). The percentage with a pH < 4 just failed to be significantly different (13% v 8%). Hiatal hernia was also found to correlate with the presence of oesophagitis. The presence of a hiatal hernia delays the clearance of acid from the oesophagus and is associated with an increased incidence of oesophagitis.

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Year:  1993        PMID: 8323336      PMCID: PMC1029337          DOI: 10.1136/adc.68.5.662

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  28 in total

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Journal:  Arch Dis Child       Date:  1959-08       Impact factor: 3.791

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Journal:  Dig Dis Sci       Date:  1979-04       Impact factor: 3.199

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Authors:  S Cohen; L D Harris
Journal:  N Engl J Med       Date:  1971-05-13       Impact factor: 91.245

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Journal:  J Pediatr       Date:  1979-01       Impact factor: 4.406

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Authors:  D O Castell
Journal:  Ann Intern Med       Date:  1975-09       Impact factor: 25.391

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  1 in total

1.  Twenty to 40 year follow up of infantile hiatal hernia.

Authors:  B T Johnston; I J Carré; P S Thomas; B J Collins
Journal:  Gut       Date:  1995-06       Impact factor: 23.059

  1 in total

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