Literature DB >> 7615264

Twenty to 40 year follow up of infantile hiatal hernia.

B T Johnston1, I J Carré, P S Thomas, B J Collins.   

Abstract

The aim of this study was to assess clinical and radiological findings of gastro-oesophageal reflux in adults who were diagnosed as having a hiatal hernia in infancy or early childhood. One hundred and eighteen patients with a minimum age of 20 who were diagnosed as having a hiatal hernia in childhood were interviewed; barium meal examination was performed in 96 of these cases. Ninety four patients had not required surgery for their hernia. The hiatal hernia persisted in 53% of these patients and 46% experienced heartburn at least monthly but in only three was this severe. Heartburn was significantly more common in patients in whom reflux was seen on barium meal. The consumption of antacids was significantly lower (20% v 46%) in patients who responded well to treatment as children. Eighteen of 24 patients who underwent surgery as children experienced heart-burn monthly but in only one patient was this severe. Two patients underwent endoscopy at their request because of symptoms during this follow up. Both had Barrett's oesophagus. In conclusion, despite the persistence of the hiatal hernia in half of the non-surgically treated patients, few complained of significant symptoms. Effective treatment in childhood was associated with a significant reduction in antacid consumption for heartburn as adults. The finding of Barrett's oesophagus in two patients high-lights a possible role for endoscopic screening in this patient group.

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Year:  1995        PMID: 7615264      PMCID: PMC1382613          DOI: 10.1136/gut.36.6.809

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  18 in total

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  3 in total

1.  Guidelines for the management of hiatal hernia.

Authors:  Geoffrey Paul Kohn; Raymond Richard Price; Steven R DeMeester; Jörg Zehetner; Oliver J Muensterer; Ziad Awad; Sumeet K Mittal; William S Richardson; Dimitrios Stefanidis; Robert D Fanelli
Journal:  Surg Endosc       Date:  2013-09-10       Impact factor: 4.584

2.  Familial hiatal hernia in a large five generation family confirming true autosomal dominant inheritance.

Authors:  I J Carré; B T Johnston; P S Thomas; P J Morrison
Journal:  Gut       Date:  1999-11       Impact factor: 23.059

3.  Gastroesophageal reflux: prevalence in adults older than 28 years after correction of esophageal atresia.

Authors:  Jacqueline A Deurloo; Seine Ekkelkamp; Joep F W M Bartelsman; Fibo J W Ten Kate; Mak Schoorl; Hugo A Heij; Daniel C Aronson
Journal:  Ann Surg       Date:  2003-11       Impact factor: 12.969

  3 in total

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