Literature DB >> 8321879

Physico-chemical and bioadhesive properties of polyacrylic acid polymers.

S Anlar1, Y Capan, A A Hincal.   

Abstract

In this study, influence of several physico-chemical properties of bioadhesive polyacrylic acid poylmers (Carbopol 910, Polycarbophil, Carbopol 940 and Carbopol 934 PH) are investigated. The effect of pH on the swelling of polyacrylic acid polymers was studied at constant temperature, ionic strength and osmolality. The polymers showed the pH dependence of equilibrium swelling. The bioadhesive strength of the bond formed between surface-preswollen systems and the sublingual bovine mucus was determined by tensile experiments. It was found that the least substituted polymers Polycarbophil and Carbopol 910 with low molecular weight showed the same degree of bioadhesion while highly branched polyacrylic acid polymers Carbopol 940 and 934 PH showed reduced bioadhesion.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8321879

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  10 in total

1.  Comparative evaluation of porous versus nonporous mucoadhesive films as buccal delivery system of glibenclamide.

Authors:  Ajay Kumar; Vikas Bali; Manish Kumar; Kamla Pathak
Journal:  AAPS PharmSciTech       Date:  2013-08-30       Impact factor: 3.246

2.  Formulation, evaluation, and comparison of bilayered and multilayered mucoadhesive buccal devices of propranolol hydrochloride.

Authors:  Vishnu M Patel; Bhupendra G Prajapati; Madhabhai M Patel
Journal:  AAPS PharmSciTech       Date:  2007-03-16       Impact factor: 3.246

3.  Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets.

Authors:  S Anlar; Y Capan; O Güven; A Göğüş; T Dalkara; A A Hincal
Journal:  Pharm Res       Date:  1994-02       Impact factor: 4.200

4.  Combination Adjuvants Affect the Magnitude of Effector-Like Memory CD8 T Cells and Protection against Listeriosis.

Authors:  Woojong Lee; Autumn Larsen; Brock Kingstad-Bakke; Chandranaik B Marinaik; M Suresh
Journal:  Infect Immun       Date:  2021-06-16       Impact factor: 3.441

5.  CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus.

Authors:  Woojong Lee; Brock Kingstad-Bakke; Ross M Kedl; Yoshihiro Kawaoka; M Suresh
Journal:  J Virol       Date:  2021-07-12       Impact factor: 5.103

6.  Preparation and evaluation of mucoadhesive cefdinir microcapsules.

Authors:  Prabhakar Reddy Veerareddy; Swathi Tedla; Srinivas Reddy Banda; Suresh Bandari; Raju Jukanti
Journal:  J Adv Pharm Technol Res       Date:  2011-04

7.  Rapid removal of ammonium from domestic wastewater using polymer hydrogels.

Authors:  Heidy Cruz; Paul Luckman; Thomas Seviour; Willy Verstraete; Bronwyn Laycock; Ilje Pikaar
Journal:  Sci Rep       Date:  2018-02-13       Impact factor: 4.379

8.  Carbomer-based adjuvant elicits CD8 T-cell immunity by inducing a distinct metabolic state in cross-presenting dendritic cells.

Authors:  Woojong Lee; Brock Kingstad-Bakke; Brett Paulson; Autumn Larsen; Katherine Overmyer; Chandranaik B Marinaik; Kelly Dulli; Randall Toy; Gabriela Vogel; Katherine P Mueller; Kelsey Tweed; Alex J Walsh; Jason Russell; Krishanu Saha; Leticia Reyes; Melissa C Skala; John-Demian Sauer; Dmitry M Shayakhmetov; Joshua Coon; Krishnendu Roy; M Suresh
Journal:  PLoS Pathog       Date:  2021-01-14       Impact factor: 6.823

9.  Preparation and characterization of a sustained release buccoadhesive system for delivery of terbutaline sulfate.

Authors:  J Emami; M A Shetabboushehri; J Varshosaz; A Eisaei
Journal:  Res Pharm Sci       Date:  2013-10

10.  Designing mucoadhesive discs containing stem bark extract of Ziziphus jujuba based on Iranian traditional documents.

Authors:  Shokouhsadat Hamedi; Mohammad Reza Shams-Ardakani; Omid Sadeghpour; Gholamreza Amin; Dawood Hajighasemali; Hossein Orafai
Journal:  Iran J Basic Med Sci       Date:  2016-03       Impact factor: 2.699
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.