Literature DB >> 831261

Antimetabolic extract from the brain of the hibernating ground squirrel Citellus tridecemlineatus.

H Swan, C Schätte.   

Abstract

Extracts of subcortical brains from hibernating ground squirrels, when injected intravenously into rats, caused a mean decrease in oxygen consumption of 35 percent and a decline in body temperature of 5 degree C. The effects lasted from 75 minutes to 30 hours. Brain extracts of nonhibernating squirrels caused no significant changes in these parameters.

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Year:  1977        PMID： 831261     DOI： 10.1126/science.831261

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

Review 1.  Potential for discovery of neuroprotective factors in serum and tissue from hibernating species.

Authors:  Austin P Ross; Kelly L Drew
Journal:  Mini Rev Med Chem       Date:  2006-08       Impact factor: 3.862

2.  Effects of a number of short peptides isolated from the brain of the hibernating ground squirrel on the EEG and behavior in rats.

Authors:  D A Ignat'ev; V V Vorob'ev; R Kh Ziganshin
Journal:  Neurosci Behav Physiol       Date:  1998 Mar-Apr

3.  Identification of a pre-hibernating state in myocardium from nonhibernating chipmunks.

Authors:  N Kondo
Journal:  Experientia       Date:  1987-08-15

4.  Extracts from the brains of hibernating and alert ground squirrels: effects on cells in culture.

Authors:  D A Amorese; H Swan; J R Bamburg
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

5.  Behavioral hypothermia of a domesticated lizard under treatment of the hypometabolic agent 3-iodothyronamine.

Authors:  Kyoungbong Ha; Haksup Shin; Hyunwoo Ju; Chan-Moon Chung; Inho Choi
Journal:  Exp Anim       Date:  2016-10-31

6.  Low cardiac output as physiological phenomenon in hibernating, free-ranging Scandinavian brown bears (Ursus arctos) - an observational study.

Authors:  Peter Godsk Jørgensen; Jon Arnemo; Jon E Swenson; Jan S Jensen; Søren Galatius; Ole Frøbert
Journal:  Cardiovasc Ultrasound       Date:  2014-09-16       Impact factor: 2.062
  6 in total

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