| Literature DB >> 8310129 |
G V Kaler1, T I Lyskova, O I Shadyro, S G Samoilenko, I P Edimecheva, S L Aksentsev, S V Konev.
Abstract
The effect of gamma-irradiated solutions of carbohydrates, mainly glucose, upon Na+, K(+)-ATPase and lipid peroxidation in rat brain synaptosomal membranes was studied. The membrane damage by irradiated glucose was enhanced in the presence of Fe2+ and was diminished when a free-radical scavenger (BHT) or metal chelators (EDTA, EGTA) were present. It is suggested that a key element in the free-radical membrane damage by irradiated carbohydrates is an Fe(2+)-complex of some species of the radiolysis products. Participation of radiotoxins of carbohydrate origin in radiobiological effects is discussed.Entities:
Mesh：
Substances：
Year: 1993 PMID： 8310129 DOI： 10.1007/BF01225922
Source DB: PubMed Journal: Radiat Environ Biophys ISSN： 0301-634X Impact factor: 1.925