Literature DB >> 2822270

The role of iron in the initiation of lipid peroxidation.

G Minotti1, S D Aust.   

Abstract

Iron is required for the initiation of lipid peroxidation. Evidence is presented that lipid peroxidation requires both Fe3+ and Fe2+, perhaps with oxygen to form a Fe3+-dioxygen-Fe2+ complex. Other mechanisms of initiation, mostly involving the iron-catalyzed formation of hydroxyl radical, are described and discussed from both theoretical and experimental view points.

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Year:  1987        PMID: 2822270     DOI: 10.1016/0009-3084(87)90050-8

Source DB:  PubMed          Journal:  Chem Phys Lipids        ISSN: 0009-3084            Impact factor:   3.329


  36 in total

1.  Effects of oxyradicals on oxymyoglobin. Deoxygenation, haem removal and iron release.

Authors:  M R Prasad; R M Engelman; R M Jones; D K Das
Journal:  Biochem J       Date:  1989-11-01       Impact factor: 3.857

2.  Oxidative and non-oxidative mechanisms of neuronal cell death and apoptosis by L-3,4-dihydroxyphenylalanine (L-DOPA) and dopamine.

Authors:  R Pedrosa; P Soares-da-Silva
Journal:  Br J Pharmacol       Date:  2002-12       Impact factor: 8.739

Review 3.  Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis.

Authors:  B Halliwell
Journal:  Br J Exp Pathol       Date:  1989-12

4.  The deoxyribose assay: an assay both for 'free' hydroxyl radical and for site-specific hydroxyl radical production.

Authors:  J M Gutteridge; B Halliwell
Journal:  Biochem J       Date:  1988-08-01       Impact factor: 3.857

5.  Prooxidant and antioxidant effects of Trolox on ferric ion-induced oxidation of erythrocyte membrane lipids.

Authors:  K M Ko; P K Yick; M K Poon; S P Ip
Journal:  Mol Cell Biochem       Date:  1994-12-07       Impact factor: 3.396

6.  The mechanism of initiation of lipid peroxidation. Evidence against a requirement for an iron(II)-iron(III) complex.

Authors:  O I Aruoma; B Halliwell; M J Laughton; G J Quinlan; J M Gutteridge
Journal:  Biochem J       Date:  1989-03-01       Impact factor: 3.857

7.  The mobile ferrous iron pool in Escherichia coli is bound to a phosphorylated sugar derivative.

Authors:  R Böhnke; B F Matzanke
Journal:  Biometals       Date:  1995-07       Impact factor: 2.949

Review 8.  Metals and lipid oxidation. Contemporary issues.

Authors:  K M Schaich
Journal:  Lipids       Date:  1992-03       Impact factor: 1.880

9.  Ferric ion-induced lipid peroxidation in erythrocyte membranes: effects of phytic acid and butylated hydroxytoluene.

Authors:  K M Ko; D V Godin
Journal:  Mol Cell Biochem       Date:  1990-06-25       Impact factor: 3.396

10.  Iron- and ascorbic acid-induced lipid peroxidation in renal microsomes isolated from rats treated with platinum compounds.

Authors:  J Hannemann; J Duwe; K Baumann
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

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