| Literature DB >> 8304341 |
V L Goei1, S Parimoo, A Capossela, T W Chu, J R Gruen.
Abstract
It has previously been shown that cDNA hybridization selection can identify and recover novel genes from large cloned genomic DNA such as cosmids or YACs. In an effort to identify candidate genes for hemochromatosis, this technique was applied to a 320-kb YAC containing the HLA-A gene. A short fragment cDNA library derived from human duodenum was selected with the YAC DNA. Ten novel gene fragments were isolated, characterized, and localized on the physical map of the YAC.Entities:
Mesh:
Substances:
Year: 1994 PMID: 8304341 PMCID: PMC1918154
Source DB: PubMed Journal: Am J Hum Genet ISSN: 0002-9297 Impact factor: 11.025