Literature DB >> 8303210

Faecal calprotectin: a novel test for the diagnosis of colorectal cancer?

A G Røseth1, J Kristinsson, M K Fagerhol, H Schjønsby, E Aadland, K Nygaard, B Roald.   

Abstract

Calprotectin, a prominent cytosol protein in neutrophil granulocytes, was present in increased concentrations in stools from 50 of 53 patients with colorectal cancer, 32 of 40 patients with colorectal polyps, and all of 18 patients with gastric cancer. After radical surgery, faecal calprotectin levels reverted to the normal range in all but one patient with colorectal cancer. Calprotectin determinations are simplified by the stability of this protein in stools. Reliable estimates can be obtained in samples of only 5 g. On the basis of data from the literature, the test for calprotectin seems better than that for occult blood for the detection of gastrointestinal neoplasms.

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Year:  1993        PMID： 8303210     DOI： 10.3109/00365529309098312

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN： 0036-5521            Impact factor:   2.423


  32 in total

Review 1.  The status of diagnostic markers for inflammatory bowel disease.

Authors:  Poonam Beniwal; Laura Harrell
Journal:  Curr Gastroenterol Rep       Date:  2010-12

Review 2.  Non-invasive investigation of inflammatory bowel disease.

Authors:  J A Tibble; I Bjarnason
Journal:  World J Gastroenterol       Date:  2001-08       Impact factor: 5.742

Review 3.  Functional and clinical aspects of the myelomonocyte protein calprotectin.

Authors:  B Johne; M K Fagerhol; T Lyberg; H Prydz; P Brandtzaeg; C F Naess-Andresen; I Dale
Journal:  Mol Pathol       Date:  1997-06

4.  A simplified, non-invasive fecal-based DNA integrity assay and iFOBT for colorectal cancer detection.

Authors:  Murugan Kalimutho; Giovanna Del Vecchio Blanco; Micaela Cretella; Elena Mannisi; Pierpaolo Sileri; Amanda Formosa; Francesco Pallone; Giorgio Federici; Sergio Bernardini
Journal:  Int J Colorectal Dis       Date:  2011-01-12       Impact factor: 2.571

Review 5.  Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update.

Authors:  Cansel Turkay; Benan Kasapoglu
Journal:  Clinics (Sao Paulo)       Date:  2010-02       Impact factor: 2.365

6.  Faecal calprotectin levels in a high risk population for colorectal neoplasia.

Authors:  O Kronborg; M Ugstad; P Fuglerud; B Johne; J Hardcastle; J H Scholefield; K Vellacott; V Moshakis; J R Reynolds
Journal:  Gut       Date:  2000-06       Impact factor: 23.059

Review 7.  Fecal calprotectin use in inflammatory bowel disease and beyond: A mini-review.

Authors:  Bashaar Alibrahim; Mohammed I Aljasser; Baljinder Salh
Journal:  Can J Gastroenterol Hepatol       Date:  2015-04

8.  Fecal calprotectin and elastase 1 determinations in patients with pancreatic diseases: a possible link between pancreatic insufficiency and intestinal inflammation.

Authors:  Raffaele Pezzilli; Alessandra Barassi; Antonio M Morselli-Labate; Lorenzo Fantini; Paola Tomassetti; Davide Campana; Riccardo Casadei; Sergio Finazzi; Gianvico Melzi d'Eril; Roberto Corinaldesi
Journal:  J Gastroenterol       Date:  2007-09-25       Impact factor: 7.527

9.  Calprotectin as a diagnostic tool for inflammatory bowel diseases.

Authors:  Marianthi Chatzikonstantinou; Panagiotis Konstantopoulos; Spyros Stergiopoulos; Konstantinos Kontzoglou; Christos Verikokos; Despina Perrea; Dimitris Dimitroulis
Journal:  Biomed Rep       Date:  2016-09-07

10.  Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma.

Authors:  Frank Serge Lehmann; Francesca Trapani; Ida Fueglistaler; Luigi Maria Terracciano; Markus von Flüe; Gieri Cathomas; Andreas Zettl; Pascal Benkert; Daniel Oertli; Christoph Beglinger
Journal:  World J Gastroenterol       Date:  2014-05-07       Impact factor: 5.742
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