Literature DB >> 8293111

[Extracellular DNA of blood after irradiation].

V G Vladimirov, L I Tishchenko, E A Surkova, I N Vasiléva.   

Abstract

It has been shown that blood extracellular DNA of irradiated rats largely consists of the low-molecular DNA and its oligomers. Molecular masses of oligomers are multiple to molecular mass of monomer fragment with nucleosome size. The low-molecular DNA has linear form. The average content of GC-pairs in low-molecular DNA is higher than in total rat's DNA (48.5% against 41.5%). The low-molecular DNA is a part of complex containing RNA, acidic proteins and lipids. It is assumed that the formation of low-molecular DNA is a result of Ca/Mg-dependent nuclear endonuclease action.

Entities:  

Mesh:

Substances:

Year:  1993        PMID: 8293111

Source DB:  PubMed          Journal:  Radiats Biol Radioecol        ISSN: 0869-8031


  3 in total

1.  A new manifestation of radiation adaptive response: low doses of ionizing radiation decrease serum DNA content under subsequent irradiation of mice in vivo with a high doze.

Authors:  V E Balakin; O E Trubetskaya; K Yu Reznikov; O I Reznikova; S I Zaichkina; O M Rozanova; A Kh Akhmadieva; E N Smirnova
Journal:  Dokl Biochem Biophys       Date:  2006 Jan-Feb       Impact factor: 0.788

2.  A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma.

Authors:  L Zhang; M Zhang; S Yang; Y Cao; S Bingrong Zhang; L Yin; Y Tian; Y Ma; A Zhang; P Okunieff; L Zhang
Journal:  Br J Radiol       Date:  2010-08       Impact factor: 3.039

3.  B1 sequence-based real-time quantitative PCR: a sensitive method for direct measurement of mouse plasma DNA levels after gamma irradiation.

Authors:  Hengshan Zhang; Steven B Zhang; Weimin Sun; Shanmin Yang; Mei Zhang; Wei Wang; Chaomei Liu; Kunzhong Zhang; Steven Swarts; Bruce M Fenton; Peter Keng; David Maguire; Paul Okunieff; Lurong Zhang
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-08-01       Impact factor: 7.038

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.