| Literature DB >> 8286421 |
K B Rank1, P K Harris, L C Ginsberg, S R Stapleton.
Abstract
A 935 bp fragment of the rat glucose-6-phosphate dehydrogenase (G6PDH) gene containing promoter activity was isolated using the polymerase chain reaction (PCR). This fragment was sequenced and primer extension analysis showed a transcription initiation site in agreement with the human and mouse genes. Computer analysis of the sequence showed a 60% and 78% similarity to the human and mouse G6PDH sequences, respectively. A TATA box element, TTAAAT, was found and shown to be 100% similar to the human and mouse TATA box elements. Based on sequence comparison, some putative transcriptional regulatory elements were also found.Entities:
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Year: 1994 PMID： 8286421 DOI： 10.1016/0167-4781(94)90128-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002