Literature DB >> 8279954

Combination effect on HIV infection in vitro of soluble CD4 and HIV-neutralizing antibodies.

J E Hansen1, A M Sørensen, S Olofsson, E Osinaga, A Roseto.   

Abstract

In combination with HIV gp120 V3-loop antibody, two carbohydrate specific neutralizing antibodies (83D4 and 2G12) had a synergistic neutralizing effect on HIV infection. However, sCD4 and an antibody which blocks gp 120/CD4 binding (1B1) both displayed antagonism.

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Year:  1994        PMID： 8279954     DOI： 10.1007/bf01379116

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  12 in total

1.  Two major groups of neutralizing anti-gp120 antibodies exist in HIV-infected individuals. Evidence for epitope diversity around the CD4 attachment site.

Authors:  S Chamat; P Nara; L Berquist; A Whalley; W J Morrow; H Köhler; C Y Kang
Journal:  J Immunol       Date:  1992-07-15       Impact factor: 5.422

2.  Passive immunization for the prevention and treatment of HIV infection.

Authors:  S Zolla-Pazner; M K Gorny
Journal:  AIDS       Date:  1992-11       Impact factor: 4.177

3.  Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein.

Authors:  M Thali; C Furman; B Wahren; M Posner; D D Ho; J Robinson; J Sodroski
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1992

4.  Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors.

Authors:  T C Chou; P Talalay
Journal:  Adv Enzyme Regul       Date:  1984

5.  Inhibition of human immunodeficiency virus (HIV) infection in vitro by anticarbohydrate monoclonal antibodies: peripheral glycosylation of HIV envelope glycoprotein gp120 may be a target for virus neutralization.

Authors:  J E Hansen; H Clausen; C Nielsen; L S Teglbjaerg; L L Hansen; C M Nielsen; E Dabelsteen; L Mathiesen; S I Hakomori; J O Nielsen
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

6.  Broadly neutralizing antibodies targeted to mucin-type carbohydrate epitopes of human immunodeficiency virus.

Authors:  J E Hansen; C Nielsen; M Arendrup; S Olofsson; L Mathiesen; J O Nielsen; H Clausen
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

7.  Carbohydrate determinant NeuAc-Gal beta (1-4) of N-linked glycans modulates the antigenic activity of human immunodeficiency virus type 1 glycoprotein gp120.

Authors:  A Bolmstedt; S Olofsson; E Sjögren-Jansson; S Jeansson; I Sjöblom; L Akerblom; J E Hansen; S L Hu
Journal:  J Gen Virol       Date:  1992-12       Impact factor: 3.891

8.  Synergistic neutralization of HIV-1 by human monoclonal antibodies against the V3 loop and the CD4-binding site of gp120.

Authors:  S A Tilley; W J Honnen; M E Racho; T C Chou; A Pinter
Journal:  AIDS Res Hum Retroviruses       Date:  1992-04       Impact factor: 2.205

9.  A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera.

Authors:  V Ghetie; T Wheeler; D Scott; J W Uhr; E S Vitetta
Journal:  AIDS Res Hum Retroviruses       Date:  1992-11       Impact factor: 2.205

10.  Purification and characterisation of a breast-cancer-associated glycoprotein not expressed in normal breast and identified by monoclonal antibody 83D4.

Authors:  G Pancino; E Osinaga; C Charpin; D Mistro; J P Barque; A Roseto
Journal:  Br J Cancer       Date:  1991-03       Impact factor: 7.640
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  3 in total

1.  Additive effects characterize the interaction of antibodies involved in neutralization of the primary dualtropic human immunodeficiency virus type 1 isolate 89.6.

Authors:  F Verrier; A Nádas; M K Gorny; S Zolla-Pazner
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

Review 2.  Multiantibody strategies for HIV.

Authors:  Andrew Hiatt; Larry Zeitlin; Kevin J Whaley
Journal:  Clin Dev Immunol       Date:  2013-06-06

Review 3.  Neutralization interfering antibodies: a "novel" example of humoral immune dysfunction facilitating viral escape?

Authors:  Mancini Nicasio; Giuseppe Sautto; Nicola Clementi; Roberta A Diotti; Elena Criscuolo; Matteo Castelli; Laura Solforosi; Massimo Clementi; Roberto Burioni
Journal:  Viruses       Date:  2012-09-24       Impact factor: 5.048
  3 in total

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