Literature DB >> 82795

Maternal rubella at St. Thomas' Hospital: is there a need to change British vaccination policy?

P N Goldwater, J R Quiney, J E Banatvala.   

Abstract

During the 28 weeks starting April 3, 1978, 269 pregnant women were assessed serologically because of exposure to or development of rubella-like illnesses, this number being four times greater than that during either of the previous 2 years. Only 33 (12%) of these patients had previously been given rubella vaccine. Rubella was confirmed serologically in 17 patients; among patients attending antenatal clinics the overall risk of acquiring infection was about 1 in 155. The mean age of patients acquiring maternal rubella was 27.9 years, and all but 1 had left school before the rubella vaccination programme started. 55 (92%) of 60 household contacts were children, of whom 24 (40%) were of preschool age and 13 (21.7%) aged less than 2 years. The interval between contact and presentation for serological studies was often long and, because of this, 79 sera had to be tested for virus-specific IgM. No drastic change in rubella vaccination policy is required but there should be more emphasis on vaccination of women of childbearing age.

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Year:  1978        PMID: 82795     DOI: 10.1016/s0140-6736(78)92055-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  4 in total

1.  Rubella vaccination: remaining problems.

Authors:  J E Banatvala
Journal:  Br Med J (Clin Res Ed)       Date:  1982-05-01

2.  Rubella susceptibility in inner-city adolescents: the effect of a school immunization law.

Authors:  D B Nelson; M M Layde; T B Chatton
Journal:  Am J Public Health       Date:  1982-07       Impact factor: 9.308

3.  Is post partum rubella vaccination worthwhile?

Authors:  P D Griffiths; C Baboonian
Journal:  J Clin Pathol       Date:  1982-12       Impact factor: 3.411

4.  Rubella antibody determination from heparinised finger-tip blood by single radial haemolysis and enzyme immunoassay.

Authors:  A Vaheri; P Väänänen; E M Salonen; J Suni
Journal:  J Clin Pathol       Date:  1980-09       Impact factor: 3.411

  4 in total

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