Literature DB >> 8270485

Adenophostins A and B: potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

M Takahashi1, T Kagasaki, T Hosoya, S Takahashi.   

Abstract

New inositol-1,4,5-trisphosphate (InsP3) agonists, adenophostins A(1) and B(2), were isolated from the culture broth of Penicillium brevicompactum SANK 11991 and SANK 12177. Its structures were related to adenine nucleotides. The agonistic activity of adenophostins A or B for binding to the InsP3 receptor was higher than InsP3 itself.

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Year:  1993        PMID： 8270485     DOI： 10.7164/antibiotics.46.1643

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  12 in total

1.  Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.

Authors:  Ana M Rossi; Kana M Sureshan; Andrew M Riley; V L Potter; Colin W Taylor
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

2.  Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides.

Authors:  Hidehisa Someya; Taiki Itoh; Mebae Kato; Shin Aoki
Journal:  J Vis Exp       Date:  2018-07-26       Impact factor: 1.355

3.  Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A.

Authors:  Kana M Sureshan; Andrew M Riley; Mark P Thomas; Stephen C Tovey; Colin W Taylor; Barry V L Potter
Journal:  J Med Chem       Date:  2012-02-08       Impact factor: 7.446

4.  The discovery and development of IP3 receptor modulators: an update.

Authors:  Jessica Gambardella; Marco B Morelli; Xujun Wang; Vanessa Castellanos; Pasquale Mone; Gaetano Santulli
Journal:  Expert Opin Drug Discov       Date:  2021-01-06       Impact factor: 7.050

5.  Triazolophostins: a library of novel and potent agonists of IP3 receptors.

Authors:  Amol M Vibhute; Vera Konieczny; Colin W Taylor; Kana M Sureshan
Journal:  Org Biomol Chem       Date:  2015-06-28       Impact factor: 3.876

6.  Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells.

Authors:  Mi Jin Yoon; A Reum Lee; Soo Ah Jeong; You-Sun Kim; Jin Yeop Kim; Yong-Jun Kwon; Kyeong Sook Choi
Journal:  Oncotarget       Date:  2014-08-30

7.  Synthesis of dimeric analogs of adenophostin A that potently evoke Ca2+ release through IP3 receptors.

Authors:  Amol M Vibhute; Poornenth Pushpanandan; Maria Varghese; Vera Koniecnzy; Colin W Taylor; Kana M Sureshan
Journal:  RSC Adv       Date:  2016-09-05       Impact factor: 3.361

8.  Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues.

Authors:  Huma Saleem; Stephen C Tovey; Andrew M Riley; Barry V L Potter; Colin W Taylor
Journal:  PLoS One       Date:  2013-02-28       Impact factor: 3.240

9.  Synthesis of Disaccharide Nucleosides Utilizing the Temporary Protection of the 2',3'-cis-Diol of Ribonucleosides by a Boronic Ester.

Authors:  Hidehisa Someya; Taiki Itoh; Shin Aoki
Journal:  Molecules       Date:  2017-10-01       Impact factor: 4.411

10.  Both d- and l-Glucose Polyphosphates Mimic d-myo-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins(1,4,5)P3 Receptor.

Authors:  Megan L Shipton; Andrew M Riley; Ana M Rossi; Charles A Brearley; Colin W Taylor; Barry V L Potter
Journal:  J Med Chem       Date:  2020-05-06       Impact factor: 7.446
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