Literature DB >> 826839

Prostaglandin synthetase activity in kidney medulla during the development of experimental hypertension in the rat.

F Haux, R M Ingerowski, F Von Bruchhausen.   

Abstract

The activity of the Pg-E2-synthetase in the rat renal medulla was observed for a period of 27 days during the development of a hypertension by clamping of the renal artery; an increased activity of Pg-E2-synthetase with a peak on the 18th day was observed in the kidneys of the 2-kidney model (2-KM=stenosing of the left arteria renalis) and the 1-kidney model (1-KM=stenosing of the left arteria renalis and additional nephrectomy of the right kidney). The initial values of the enzyme activities were reached again on the 21st (1-KM) resp. 24th (2-KM) day post operationem.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 826839     DOI： 10.1007/BF00509776

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  13 in total

1.  THE BIOSYNTHESIS OF PROSTAGLANDINS.

Authors:  R K BEERTHUIS; D H NUGTEREN; H VONKEMAN
Journal:  Biochim Biophys Acta       Date:  1964-07-15

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Renal prostaglandin synthesis in the Goldblatt hypertensive rat.

Authors:  D J Pugsley; L J Beilin; R Peto
Journal:  Circ Res       Date:  1975-06       Impact factor: 17.367

4.  [Intensifying of experimental hypertension following prostaglandin--biosynthesis--inhibition].

Authors:  B A Schölkens
Journal:  Verh Dtsch Ges Kreislaufforsch       Date:  1974

5.  Prostaglandin synthetase activity in the renal medulla of normal and hypertensive rats.

Authors:  L Grodzińska; K Schrör; U Wartner; W Förster; R Gryglewski
Journal:  Pol J Pharmacol Pharm       Date:  1974 Jan-Apr

6.  The antihypertensive action of arachidonic acid in the spontaneous hypertensive rat and its antagonism by anti-inflammatory agents.

Authors:  M Cohen; J Sztokalo; E Hinsch
Journal:  Life Sci       Date:  1973-08-16       Impact factor: 5.037

7.  A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents.

Authors:  C Takeguchi; C J Sih
Journal:  Prostaglandins       Date:  1972-09

8.  Relationship between inhibition of prostaglandin synthesis and drug efficacy: support for the current theory on mode of action of aspirin-like drugs.

Authors:  R V Tomlinson; H J Ringold
Journal:  Biochem Biophys Res Commun       Date:  1972-01-31       Impact factor: 3.575

9.  Analysis of prostaglandins in rat vesicular glands.

Authors:  W C Tan; O S Privett
Journal:  Lipids       Date:  1972-09       Impact factor: 1.880

10.  Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism.

Authors:  J M Armstrong; G J Blackwell; R J Flower; J C McGiff; K M Mullane; J R Vane
Journal:  Nature       Date:  1976-04-15       Impact factor: 49.962
View more
  3 in total

1.  Attenuated depressor response to arachidonic acid and prostaglandins in unclipped renal hypertensive rats.

Authors:  R G Ten Berg; W De Jong; F P Nijkamp
Journal:  Br J Pharmacol       Date:  1980-03       Impact factor: 8.739

2.  Decreased prostaglandin synthetase activity during kidney regeneration after folic acid or 2,4,5-triamino-6-styrylpyrimidine application.

Authors:  R M Ingerowski; F Haux; F Bruchhausen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-06       Impact factor: 3.000

3.  (+)-Cyanidanol-3 as inhibitor of prostaglandin synthetase. Studies on renal medulla and liver of the rat in vitro and in vivo.

Authors:  J Baumann; F von Bruchhausen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-01       Impact factor: 3.000
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.