Literature DB >> 8255835

Microalbuminuria and coronary heart disease in non-diabetics.

D Buggy1, J Feely, J Murphy, C O'Sullivan, M Walsh.   

Abstract

Microalbuminuria (or urinary albumin excretion rates (AER) above normal limits) is associated with coronary heart disease (CHD) particularly in diabetics. To determine the sensitivity and specificity of AER for CHD in a non-diabetic population we prospectively studied 115 consecutive patients undergoing coronary angiography and 66 undergoing exercise electrocardiography (ECG). There was no relationship between AER and the severity of CHD determined by angiography (Gensini-scored). While microalbuminuria (AER > 20 micrograms/minute) was 91% specific it had low sensitivity (12%). Microalbuminuria is not a sensitive indicator of CHD in a non-diabetic population.

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Year:  1993        PMID: 8255835      PMCID: PMC2399781          DOI: 10.1136/pgmj.69.815.704

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  19 in total

1.  Microalbuminuria as predictor of increased mortality in elderly people.

Authors:  E M Damsgaard; A Frøland; O D Jørgensen; C E Mogensen
Journal:  BMJ       Date:  1990-02-03

2.  Screening for microalbuminuria in patients with diabetes mellitus: frozen storage of urine samples decreases their albumin content.

Authors:  L D Elving; J A Bakkeren; M J Jansen; C M de Kat Angelino; E de Nobel; P J van Munster
Journal:  Clin Chem       Date:  1989-02       Impact factor: 8.327

3.  Microalbuminuria in diabetes mellitus: more on urine storage and accuracy of colorimetric assays.

Authors:  O Giampietro; A Clerico; L Cruschelli; G Penno; R Navalesi
Journal:  Clin Chem       Date:  1989-07       Impact factor: 8.327

4.  Microalbuminuria and diabetic retinopathy.

Authors:  A H Barnett; K Dallinger; P Jennings; J Fletcher; O Odugbesan
Journal:  Lancet       Date:  1985-01-05       Impact factor: 79.321

5.  Prevention of diabetic nephropathy with enalapril in normotensive diabetics with microalbuminuria.

Authors:  M Marre; G Chatellier; H Leblanc; T T Guyene; J Menard; P Passa
Journal:  BMJ       Date:  1988-10-29

6.  Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus.

Authors:  G C Viberti; R D Hill; R J Jarrett; A Argyropoulos; U Mahmud; H Keen
Journal:  Lancet       Date:  1982-06-26       Impact factor: 79.321

7.  Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes.

Authors:  C E Mogensen
Journal:  N Engl J Med       Date:  1984-02-09       Impact factor: 91.245

8.  Predicting diabetic nephropathy in insulin-dependent patients.

Authors:  C E Mogensen; C K Christensen
Journal:  N Engl J Med       Date:  1984-07-12       Impact factor: 91.245

9.  Short term effect of captopril on microalbuminuria induced by exercise in normotensive diabetics.

Authors:  G Romanelli; A Giustina; A Cimino; U Valentini; E Agabiti-Rosei; G Muiesan; G Giustina
Journal:  BMJ       Date:  1989-02-04

10.  The prognostic significance of proteinuria: the Framingham study.

Authors:  W B Kannel; M J Stampfer; W P Castelli; J Verter
Journal:  Am Heart J       Date:  1984-11       Impact factor: 4.749

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