Literature DB >> 8254776

Long-term persistent infection of swine monocytes/macrophages with African swine fever virus.

C Carrillo1, M V Borca, C L Afonso, D V Onisk, D L Rock.   

Abstract

Long-term persistent infection was established in 100% of pigs (n = 19) experimentally infected with African swine fever virus (ASFV). Viral DNA was detected in peripheral blood mononuclear leukocytes (PBML) at greater than 500 days postinfection by a PCR assay. Infectious virus was not, however, isolated from the same PBML samples. In cell fractionation studies of PBML, monocytes/macrophages were found to harbor viral DNA during the persistent phase of infection. This result indicates that monocytes/macrophages are persistently infected with ASFV and that ASFV-swine monocyte/macrophage interactions can result in either lytic or persistent infection.

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Year:  1994        PMID： 8254776      PMCID： PMC236326     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Comparison of lesions in acute and chronic African swine fever.

Authors:  J Moulton; L Coggins
Journal:  Cornell Vet       Date:  1968-07

2.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

3.  Restriction site map of African swine fever virus DNA.

Authors:  J M Almendral; R Blasco; V Ley; A Beloso; A Talavera; E Viñuela
Journal:  Virology       Date:  1984-03       Impact factor: 3.616

4.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

5.  Porcine leukocyte cellular subsets sensitive to African swine fever virus in vitro.

Authors:  I Casal; L Enjuanes; E Viñuela
Journal:  J Virol       Date:  1984-10       Impact factor: 5.103

6.  Pathogenesis of African swine fever in young pigs.

Authors:  G S Colgrove; E O Haelterman; L Coggins
Journal:  Am J Vet Res       Date:  1969-08       Impact factor: 1.156

7.  Production and titration of African swine fever virus in porcine alveolar macrophages.

Authors:  A L Carrascosa; J F Santarén; E Viñuela
Journal:  J Virol Methods       Date:  1982-01       Impact factor: 2.014

8.  Preparation and characterization of monoclonal antibodies reactive with porcine PBL.

Authors:  M D Pescovitz; J K Lunney; D H Sachs
Journal:  J Immunol       Date:  1984-07       Impact factor: 5.422

9.  Monoclonal precipitating antibodies to porcine immunoglobulin M.

Authors:  P S Paul; R A van Deusen; W L Mengeling
Journal:  Vet Immunol Immunopathol       Date:  1985-04       Impact factor: 2.046

10.  Quantitative aspects of the transmission of African swine fever.

Authors:  J W McVicar
Journal:  Am J Vet Res       Date:  1984-08       Impact factor: 1.156
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  19 in total

1.  An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell death.

Authors:  C L Afonso; J G Neilan; G F Kutish; D L Rock
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

2.  Isolation of porcine monocyte population: a simple and efficient method.

Authors:  Christin Berg; Sebastian Wilker; Johann Roider; Alexa Klettner
Journal:  Vet Res Commun       Date:  2013-04-28       Impact factor: 2.459

3.  Novel swine virulence determinant in the left variable region of the African swine fever virus genome.

Authors:  J G Neilan; L Zsak; Z Lu; G F Kutish; C L Afonso; D L Rock
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

4.  A comparative analysis on the synonymous codon usage pattern in viral functional genes and their translational initiation region of ASFV.

Authors:  Jian-Hua Zhou; Zong-Liang Gao; Dong-Jie Sun; Yao-Zhong Ding; Jie Zhang; Laszlo Stipkovits; Susan Szathmary; Zygmunt Pejsak; Yong-Sheng Liu
Journal:  Virus Genes       Date:  2012-11-16       Impact factor: 2.332

5.  Deletion of a CD2-like gene, 8-DR, from African swine fever virus affects viral infection in domestic swine.

Authors:  M V Borca; C Carrillo; L Zsak; W W Laegreid; G F Kutish; J G Neilan; T G Burrage; D L Rock
Journal:  J Virol       Date:  1998-04       Impact factor: 5.103

6.  The African swine fever virus thymidine kinase gene is required for efficient replication in swine macrophages and for virulence in swine.

Authors:  D M Moore; L Zsak; J G Neilan; Z Lu; D L Rock
Journal:  J Virol       Date:  1998-12       Impact factor: 5.103

7.  The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Authors:  H L Lipton; G Twaddle; M L Jelachich
Journal:  J Virol       Date:  1995-04       Impact factor: 5.103

8.  Sero-prevalence and risk factors associated with African swine fever on pig farms in southwest Nigeria.

Authors:  Emmanuel Jolaoluwa Awosanya; Babasola Olugasa; Gabriel Ogundipe; Yrjo Tapio Grohn
Journal:  BMC Vet Res       Date:  2015-06-12       Impact factor: 2.741

9.  Thoughts on African Swine Fever Vaccines.

Authors:  Daniel L Rock
Journal:  Viruses       Date:  2021-05-20       Impact factor: 5.048

10.  Macrophage Polarization in Virus-Host Interactions.

Authors:  Yongming Sang; Laura C Miller; Frank Blecha
Journal:  J Clin Cell Immunol       Date:  2015-04
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