Literature DB >> 8253997

Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS.

T Mazzulli1, R H Rubin, M J Ferraro, R T D'Aquila, S A Doveikis, B R Smith, T H The, M S Hirsch.   

Abstract

We evaluated a rapid immunoperoxidase technique for the detection of cytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 specimens). Antigenemia was 92% sensitive and 98% specific for the detection of clinical CMV infection in transplant recipients and 100% sensitive and 86% specific in persons with AIDS. Overall, CMV antigenemia was a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.

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Year:  1993        PMID： 8253997      PMCID： PMC266028          DOI： 10.1128/jcm.31.10.2824-2827.1993

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  20 in total

1.  Prospective study of cytomegalovirus antigenemia in allograft recipients.

Authors:  H Miller; E Rossier; R Milk; C Thomas
Journal:  J Clin Microbiol       Date:  1991-05       Impact factor: 5.948

2.  Antigenemia in the diagnosis and monitoring of active cytomegalovirus infection after liver transplantation.

Authors:  A P van den Berg; I J Klompmaker; E B Haagsma; A Scholten-Sampson; C M Bijleveld; J Schirm; M van der Giessen; M J Slooff; T H The
Journal:  J Infect Dis       Date:  1991-08       Impact factor: 5.226

Review 3.  Cytomegalovirus antigenemia.

Authors:  T H The; W van der Bij; A P van den Berg; M van der Giessen; J Weits; H G Sprenger; W J van Son
Journal:  Rev Infect Dis       Date:  1990 Sep-Oct

4.  Recent advances in the diagnosis of active cytomegalovirus infection after organ transplantation.

Authors:  A P van den Berg; W J van Son; N M Jiwa; W van der Bij; J Schirm; M van der Giessen; T H The
Journal:  Transplant Proc       Date:  1990-02       Impact factor: 1.066

5.  Detection of human cytomegalovirus immediate early antigen in leukocytes as a marker of viremia in immunocompromised patients.

Authors:  M G Revello; E Percivalle; M Zavattoni; M Parea; P Grossi; G Gerna
Journal:  J Med Virol       Date:  1989-10       Impact factor: 2.327

6.  The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during an active cytomegalovirus infection.

Authors:  J M Grefte; B T van der Gun; S Schmolke; M van der Giessen; W J van Son; B Plachter; G Jahn; T H The
Journal:  J Gen Virol       Date:  1992-11       Impact factor: 3.891

7.  Monitoring of human cytomegalovirus infections and ganciclovir treatment in heart transplant recipients by determination of viremia, antigenemia, and DNAemia.

Authors:  G Gerna; D Zipeto; M Parea; M G Revello; E Silini; E Percivalle; M Zavattoni; P Grossi; G Milanesi
Journal:  J Infect Dis       Date:  1991-09       Impact factor: 5.226

8.  Early treatment with ganciclovir to prevent cytomegalovirus disease after allogeneic bone marrow transplantation.

Authors:  J M Goodrich; M Mori; C A Gleaves; C Du Mond; M Cays; D F Ebeling; W C Buhles; B DeArmond; J D Meyers
Journal:  N Engl J Med       Date:  1991-12-05       Impact factor: 91.245

9.  Predictive value of cytomegalovirus viraemia for the occurrence of CMV organ involvement in AIDS.

Authors:  D Salmon; F Lacassin; M Harzic; C Leport; C Perronne; F Bricaire; F Brun-Vezinet; J L Vilde
Journal:  J Med Virol       Date:  1990-11       Impact factor: 2.327

10.  Nuclear expression of the lower matrix protein of human cytomegalovirus in peripheral blood leukocytes of immunocompromised viraemic patients.

Authors:  M G Revello; E Percivalle; A Di Matteo; F Morini; G Gerna
Journal:  J Gen Virol       Date:  1992-02       Impact factor: 3.891
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  19 in total

1.  Comparison of quantitative cytomegalovirus (CMV) PCR in plasma and CMV antigenemia assay: clinical utility of the prototype AMPLICOR CMV MONITOR test in transplant recipients.

Authors:  A M Caliendo; K St George; S Y Kao; J Allega; B H Tan; R LaFontaine; L Bui; C R Rinaldo
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

2.  Value of different assays for detection of human cytomegalovirus (HCMV) in predicting the development of HCMV disease in human immunodeficiency virus-infected patients.

Authors:  B S Blank; P L Meenhorst; J W Mulder; G J Weverling; H Putter; W Pauw; W C van Dijk; P Smits; S Lie-A-Ling; P Reiss; J M Lange
Journal:  J Clin Microbiol       Date:  2000-02       Impact factor: 5.948

3.  Comparison of three assays for cytomegalovirus detection in AIDS patients at risk for retinitis.

Authors:  P Wattanamano; J L Clayton; J J Kopicko; P Kissinger; S Elliot; C Jarrott; S Rangan; M A Beilke
Journal:  J Clin Microbiol       Date:  2000-02       Impact factor: 5.948

Review 4.  Role of cell culture for virus detection in the age of technology.

Authors:  Diane S Leland; Christine C Ginocchio
Journal:  Clin Microbiol Rev       Date:  2007-01       Impact factor: 26.132

5.  Comparison of culture and the antigenemia assay for detection of cytomegalovirus in blood specimens submitted to a reference laboratory.

Authors:  B G Brumback; S N Bolejack; M V Morris; C Mohla; T E Shutzbank
Journal:  J Clin Microbiol       Date:  1997-07       Impact factor: 5.948

6.  Evaluation of the Digene Hybrid Capture System for detection and quantitation of human cytomegalovirus viremia in human immunodeficiency virus-infected patients.

Authors:  T Mazzulli; S Wood; R Chua; S Walmsley
Journal:  J Clin Microbiol       Date:  1996-12       Impact factor: 5.948

7.  High-level sensitivity of quantitative pp65 cytomegalovirus (CMV) antigenemia assay for diagnosis of CMV disease in AIDS patients and follow-up.

Authors:  B Bek; M Boeckh; J Lepenies; B Bieniek; K Arasteh; W Heise; K M Deppermann; G Bornhöft; M Stöffler-Meilicke; I Schuller; G Höffken
Journal:  J Clin Microbiol       Date:  1996-02       Impact factor: 5.948

8.  Development of a method for direct quantification of cytomegalovirus antigenemia by flow cytometry.

Authors:  B M Imbert-Marcille; N Robillard; A S Poirier; M Coste-Burel; D Cantarovich; N Milpied; S Billaudel
Journal:  J Clin Microbiol       Date:  1997-10       Impact factor: 5.948

9.  Determination of the number of blood samples needed for optimal detection of cytomegalovirus viremia in immunocompromised patients using a shell-vial assay.

Authors:  J Reina; I Blanco; M Munar
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1997-04       Impact factor: 3.267

10.  Validation of clinical application of cytomegalovirus plasma DNA load measurement and definition of treatment criteria by analysis of correlation to antigen detection.

Authors:  Jayant S Kalpoe; Aloys C M Kroes; Menno D de Jong; Janke Schinkel; Caroline S de Brouwer; Matthias F C Beersma; Eric C J Claas
Journal:  J Clin Microbiol       Date:  2004-04       Impact factor: 5.948
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